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Lactate is preferred to glucose as an energy substrate and exacerbates spiking activity in most neuron types of juvenile somatosensory cortex by closing ATP-sensitive potassium channels.

T3 is taken up by axonal termini and is retrogradely transported into endosomal vesicles to the cell nucleus, where it regulates gene expression.

Glutamatergic neurons lacking the mitochondrial pyruvate carrier show reduced M-type potassium channel activity and hyperexcitability upon intense firing.

Glutamatergic brainstem neurons drive motor and respiratory deficits, and GABAergic basal ganglia neurons cause hypothermia and fatal epileptic events, in a model of mitochondrial disease.

Characterization of an abundant clonogenic and multipotent population of immature neuroblasts, at the transition between transient-amplifying progenitor (TAP) neuroblasts and migratory neuroblasts, reversibly engaged in neuronal differentiation.

The nerve growth-repellent activity that generates spinal nerve repeat-patterning in birds and mammals is identified at the molecular level, and a similar system is revealed in adult brain grey matter.

Endothelial tightening by augmenting low level Wnt/β-catenin activity in vessels of the mouse subfornical organ, influences neuronal activation in water-deprived mice, linking endothelial barrier properties to neuro-vascular coupling.

The endoplasmic reticulum (ER)-resident protein wolframin regulates MCT1 protein levels in retinal glial cells controlling the shuttling of energy metabolites to both somata and axons of retinal ganglion cells and, thus, supporting their fitness and survival.