9 results found
    1. Developmental Biology
    2. Neuroscience

    Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification

    Jing Zhao, Quan Lin ... Yi Sun
    During neurogenesis, Neurogenin 1 activates the microRNA miR-9, which directly targets the Jak-Stat pathway to inhibit astrogliogenesis.
    1. Developmental Biology
    2. Neuroscience

    Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway

    Mahima Bose, Ishita Talwar ... Shubha Tole
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia

    Maria Ardaya, Marie-Catherine Tiveron ... Fabio Cavaliere
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons

    Matthieu Genestine, Daisy Ambriz ... Edmund Au
    Species-specific timing of interneuron migration across mice and humans is regulated by two vascular-derived factors, SPARC and SerpinE1.
    1. Neuroscience

    DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation

    Laura Morcom, Timothy J Edwards ... Linda J Richards
    Incomplete interhemispheric fissure remodelling determines corpus callosum size in humans and BTBR N2 mice that carry a deletion in Draxin.
    1. Cell Biology
    2. Neuroscience

    Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia

    Lauritz Kennedy, Emilie R Glesaaen ... Johanne E Rinholm
    HCAR1 knockout mice are unable to initiate brain tissue repair after a hypoxic-ischemic injury.
    1. Stem Cells and Regenerative Medicine

    Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation

    Rubens Sautchuk, Brianna H Kalicharan ... Roman A Eliseev
    Promoter studies identified BMP/Smad signaling as a transcriptional regulator of Ppif gene encoding cyclophilin D, a component of the mitochondrial permeability transition pore, and gain- and loss-of-function experiments determined how such regulation affects osteogenic differentiation.
    1. Developmental Biology
    2. Neuroscience

    DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

    Laura Morcom, Ilan Gobius ... Linda J Richards
    Axon guidance molecules DCC and NTN1 regulate astroglial-mediated interhemispheric remodelling required for corpus callosum formation in humans and mice.
    1. Stem Cells and Regenerative Medicine

    Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair

    Francisca Benavente, Katja M Piltti ... Aileen Anderson
    Complement C1q directly drives the behavior of human neural stem cells via a classical receptor signaling mechanism modulating their capacity for functional integration in vivo.

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