Quantitative live-cell time-lapse imaging reveals that the spatial and temporal degree of cortical polarity domains reflects stem-cell division capacity in cells of the Arabidopsis plant leaf epidermis.

The stem cell orientation checkpoint senses the correct orientation of centrosomes via their interactions with a protein called Bazooka.

The Par complex controls spindle orientation during asymmetric cell division by phosphorylating the tumor suppressor Discs large, overcoming its autoinhibited state, and allowing it to bind the microtubule-binding protein GukHolder.

Asymmetric cell division is linked to cell-specific transcription by handoff of a key developmental regulator from the cytokinetic machinery to the adjacent cell pole where it oligomerizes to become stabilized and activated.

Receptors for two distinct pathways are linked to choreograph the dynamic interaction of Wnt on the stem cell membrane, which leads to the control of asymmetric cell division.

A novel long non-coding RNA targets microRNA miR-34a for epigenetic silencing and initiates asymmetric division of colon cancer stem cells.

A separation-of-function mutation reveals that a niche ligand receptor Dome functions in spindle orientation during asymmetric stem cell division by directly binding to Eb1, independent of its role in downstream JAK-STAT signaling.

Systematic analysis of C. elegans zygotes manipulated to divide equally demonstrates that daughter cell size asymmetry is critical for proper cell cycle timing, positioning, and fates during subsequent embryogenesis.

The formation of stomatal 'helper cells' (=subsidiary cells) in grasses requires two opposing polarity domains with diverse roles in establishing division asymmetry.

Mammalian neural stem cells specifically regulate a subset of astral microtubules to govern the subtle changes in spindle orientation that underlie symmetric vs asymmetric cell division during embryonic cortical neurogenesis.