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    1. Developmental Biology
    2. Neuroscience

    Vibrator and PI4KIIIα govern neuroblast polarity by anchoring non-muscle myosin II

    Chwee Tat Koe, Ye Sing Tan ... Hongyan Wang
    Vibrator and PI4KIIIα that stimulate the synthesis of PI(4)P anchor non-muscle myosin II RLC (Sqh) to the plasma membrane and conversely Sqh associates with PI(4)P and facilitates its membrane localization during asymmetric division of neuroblasts.
    1. Neuroscience

    Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky

    Katrin Franke, Chenchen Cai ... Andreas Savas Tolias
    Widespread color-opponency in mouse V1 enhances object decoding in the sky, highlighting the evolutionary importance of color processing in non-primate species.
    1. Cell Biology
    2. Developmental Biology

    Par3 cooperates with Sanpodo for the assembly of Notch clusters following asymmetric division of Drosophila sensory organ precursor cells

    Elise Houssin, Mathieu Pinot ... Roland Le Borgne
    Baz/Par3 and Sanpdo are required for clustering and activation of Notch receptors to allow intra-lineage private communication following asymmetric division of Drosophila epithelial cells.
    1. Cell Biology

    Vacuolar H+-ATPase determines daughter cell fates through asymmetric segregation of the nucleosome remodeling and deacetylase complex

    Zhongyun Xie, Yongping Chai ... Wei Li
    Asymmetric segregation of V-ATPase may cause distinct acidification levels in the two daughter cells, enabling asymmetric epigenetic inheritance that specifies their respective life-versus-death fates.
    1. Developmental Biology

    Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

    Jennifer J Banerjee, Birgit L Aerne ... Nicolas Tapon
    Meru is a factor that provides tissue-specific information to the core polarity machinery by linking planar to apical-basal polarity in asymmetrically dividing sensory organ precursors.
    1. Stem Cells and Regenerative Medicine

    Klp10A, a stem cell centrosome-enriched kinesin, balances asymmetries in Drosophila male germline stem cell division

    Cuie Chen, Mayu Inaba ... Yukiko M Yamashita
    Microtubule-depolymerizing kinesin, Klp10A, prevents overgrowth of the mother centrosome to prevent undesirable asymmetries during asymmetric divisions of Drosophila male germline stem cells.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Asymmetric localization of the cell division machinery during Bacillus subtilis sporulation

    Kanika Khanna, Javier Lopez-Garrido ... Elizabeth Villa
    During sporulation, FtsAZ filaments mediating cell division in Bacillus subtilis are positioned asymmetrically around the septum only on the mother cell side, making the septum thinner than during vegetative growth.
    1. Cell Biology
    2. Developmental Biology

    Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle

    Chet Huan Oon, Kenneth E Prehoda
    Neural stem cells dynamically polarize through the stepwise activity of polarized cortical targeting and cortical flows that coalescence discontinuous cortical patches into an organized cap structure.
    1. Cell Biology

    A sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cell

    Lori Clay, Fabrice Caudron ... Yves Barral
    Sphingolipids govern the compartmentalization of yeast cells through the assembly of lateral diffusion barriers in ER membranes.
    1. Developmental Biology

    The evolutionary modifications of a GoLoco motif in the AGS protein facilitate micromere formation in the sea urchin embryo

    Natsuko Emura, Florence DM Wavreil ... Mamiko Yajima
    Activator of G-protein signaling C-terminus serves as a variable element to induce asymmetric cell division, facilitating developmental diversity among species.