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    1. Developmental Biology
    2. Neuroscience

    Neuronal cell fate diversification controlled by sub-temporal action of Kruppel

    Johannes Stratmann et al.
    A combination of temporal and sub-temporal genes combine to move the stem cell through different competence windows to generate different cell types at different time-points in Drosophila.
    1. Neuroscience

    The nature of the animacy organization in human ventral temporal cortex

    Sushrut Thorat et al.
    The animacy organization in human ventral visual cortex is driven by both the presence of animal-diagnostic visual features and the psychological property of agency.
    1. Cancer Biology
    2. Cell Biology

    A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing

    Francesca Angiolini et al.
    Endothelial cells express a soluble isoform of the L1CAM cell adhesion molecule that is generated by the splicing factor NOVA2 and induces angiogenesis, with relevant implications for ovarian cancer vascularization.
    1. Computational and Systems Biology

    Spatiotemporal establishment of dense bacterial colonies growing on hard agar

    Mya R Warren et al.
    A 3D model captures the growth and expansion dynamics of bacterial colonies, revealing distinct effects of surface tension, mechanical forces, and nutrients on the speed of radial and vertical expansion.
    1. Neuroscience

    Distinct spatial coordinate of visual and vestibular heading signals in macaque FEFsem and MSTd

    Lihua Yang, Yong Gu
    In both frontal and temporal–parietal visual cortices of macaque, distinct spatial coordinates of visual and vestibular signals are predominantly eye centered and head centered, respectively.
    1. Structural Biology and Molecular Biophysics

    Domain–domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel

    Mark A Zaydman et al.
    Contrary to a generally accepted principle, the pore properties of KCNQ1 channels depend on the states of voltage-sensing domains activation; KCNE1 alters the voltage-sensing domains-pore coupling to modulate KCNQ1 channel properties.
  1. Annual Report: 2019 in review

    We reflect on eLife’s efforts to transform research communication through improvements to science publishing, technology and research culture.
  2. Event Report: Aging, Geroscience and Longevity Symposium

    Catch up on our online symposium in which eLife authors showcased their research from the upcoming Aging, Geroscience and Longevity Special Issue.
  3. eLife Ambassadors: Staying active on many different fronts

    From funding and scientific publishing to outreach and the environmental impact of research, eLife Ambassadors continue to work on a wide range of activities.
  4. Peer Review Week 2018: eLife thanks reviewers for their contributions

    4,845 researchers reviewed 2,392 full submissions to eLife in the last year, helping to increase collaboration and transparency within the review process.