A critical assessment of published microRNA/microRNA-like provides clues on features and conservation of these hairpin RNAs in fungi in addition to a centralized loci annotation resource for the community.

Faithful models of RMC require SMARCB1 loss for survival, and genetic and small-molecule screens identify inhibition of the ubiquitin-proteasome system (UPS) as a potential therapeutic approach for SMARCB1 deficient cancers.

Non-canonical ‘testis-specific’ actin-related protein (Arp), Arp53D, is critical for early embryonic development in Drosophila, revealing important roles for lineage-specific, divergent, testis-expressed non-canonical Arps outside the male germline in animals.

DIP2 is a conserved protein across fungi and animals that regulates specific diacylglycerol pools by diverting them to storage lipid biosynthesis to enable cellular homeostasis and adaptations.

Sensory innervation density in the insect associative learning center is set by postsynaptic cells and accomplished by flexible allocation of processes by presynaptic cells.

A genome analysis of Xenoturbella bocki provides insights into the biology of this enigmatic marine worm and enhances our understanding of early bilaterian evolution.

An improved conditional gene-based association analysis framework guided by multiple variant-gene mapping strategies was built and evaluated based on its performance in predicting the potential susceptibility isoforms, genes, and tissues of schizophrenia.

Individual participant data meta-analysis reveals the estimated lifespan trajectory of cortical GABA, characterized by an early rapid increase, followed by a period of stability during early adulthood, and a gradual decrease.

Robotic AI system automated discovery of optimum cell culture protocol, a most experience-dependent process in regenerative medicine.

By participating in the microglomerular microcircuit in the Drosophila mushroom body calyx, the anterior paired lateral neuron normalizes odour-evoked representations at the calyx via inhibition proportional to the input strength and localized to the regions where those inputs are positioned.