88 results found
    1. Human Biology and Medicine
    2. Neuroscience

    Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss

    Adelaida M Celaya et al.
    Mitogen-activated protein kinase phosphatase 1 (DUSP1) deficiency causes early redox imbalance and increased inflammatory response in the cochlea, leading to cell loss and progressive neurosensory hearing loss.
    1. Neuroscience

    Generalization of learned responses in the mormyrid electrosensory lobe

    Conor Dempsey et al.
    In vivo recordings and computational modeling of the electrosensory lobe of mormyrid fish provide a circuit-level description of how learning generalizes to new situations.
    1. Neuroscience

    Behavioural and neural signatures of perceptual decision-making are modulated by pupil-linked arousal

    Jochem van Kempen et al.
    A direct relationship between pupil diameter and electrophysiological correlates of attention, sensory stimulus processing and target detection was observed demonstrating that arousal has a substantial influence on perceptual decision-making.
    1. Neuroscience

    Ventrolateral periaqueductal gray neurons prioritize threat probability over fear output

    Kristina M Wright, Michael A McDannald
    Single-unit activity in the ventrolateral periaqueductal gray, a brain region implicated in organizing fear output, is found to reflect threat probability, a more versatile threat signal.
    1. Neuroscience

    Control of entropy in neural models of environmental state

    Timothy H Muller et al.
    Evidence for neuromodulatory control of flexibility in human neural models.
    1. Neuroscience

    Parallel pathways for sound processing and functional connectivity among layer 5 and 6 auditory corticofugal neurons

    Ross S Williamson, Daniel B Polley
    Targeted recordings from subcortical projection neurons in the auditory cortex reveal two cell classes with distinct signatures of sensory processing and different patterns of local and long-range connectivity.
    1. Neuroscience

    High-order thalamic inputs to primary somatosensory cortex are stronger and longer lasting than cortical inputs

    Wanying Zhang, Randy M Bruno
    Secondary thalamic nuclei may provide stronger, longer-lasting input to superficial layers of primary sensory cortex than other cortical areas can.
    1. Developmental Biology
    2. Neuroscience

    Embryonic Development: The evolution of hearing and balance

    Forrest P Weghorst, Karina S Cramer
    New genetic tools have allowed researchers to compare how the brainstem auditory and vestibular nuclei develop in embryonic chicks and mice.
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