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    1. Neuroscience

    Cell-specific gain modulation by synaptically released zinc in cortical circuits of audition

    Charles T Anderson, Manoj Kumar ... Thanos Tzounopoulos
    Synaptic zinc is a novel modulator of cortical sound processing - a modulator that increases the gain of principal neurons, but reduces the gain of interneurons.
    1. Evolutionary Biology

    Morphometric analysis of lungfish endocasts elucidates early dipnoan palaeoneurological evolution

    Alice M Clement, Tom J Challands ... John A Long
    Cranial endocasts of fossil and extant lungfish, analysed via tomography and novel principle component analyses designed for use with missing data, show that lungfish forebrain and inner ear regions show the most variation in brain shape evolution through time.
    1. Neuroscience

    Noise-induced plasticity of KCNQ2/3 and HCN channels underlies vulnerability and resilience to tinnitus

    Shuang Li, Bopanna I Kalappa, Thanos Tzounopoulos
    Mice that successfully avoid developing tinnitus despite exposure to excessive noise show spontaneous recovery of KCNQ2/3 potassium channel activity associated with a reduction in HCN channel activity in auditory brainstem neurons.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Neural circuit-wide analysis of changes to gene expression during deafening-induced birdsong destabilization

    Bradley M Colquitt, Kelly Li ... Michael S Brainard
    Large-scale gene expression analysis of the songbird brain identifies the molecular and cellular features of vocal motor circuits that are altered by the loss of hearing.
    1. Neuroscience

    Membrane properties specialize mammalian inner hair cells for frequency or intensity encoding

    Stuart L Johnson
    Mammalian primary sensory inner hair cells play an active role in auditory information processing, such that they show a preference for either timing or intensity coding.
    1. Neuroscience

    Neurexins control the strength and precise timing of glycinergic inhibition in the auditory brainstem

    He-Hai Jiang, Ruoxuan Xu ... Fujun Luo
    Neurexins are essential for shaping the functional properties of glycinergic synapse in the auditory brainstem, further attesting their universal role as critical presynaptic organizers in all major fast chemical synapses.
    1. Neuroscience

    Timing of the reticular lamina and basilar membrane vibration in living gerbil cochleae

    Wenxuan He, David Kemp, Tianying Ren
    Heterodyne low-coherence interferometry demonstrates that the latency of the sound-induced reticular lamina vibration is significantly greater than that of the basilar membrane vibration in living gerbil cochleae.
    1. Neuroscience

    Drosophila mechanical nociceptors preferentially sense localized poking

    Zhen Liu, Meng-Hua Wu ... Xin Liang
    A fly larval mechanical nociceptor develops dedicated neuronal mechanisms to support its sensory preference in detecting localized poking forces, and this sensory feature well supports the physiological function of the nociceptor in sensing the physical attack of its natural enemy.
    1. Neuroscience

    Functional connectivity in human auditory networks and the origins of variation in the transmission of musical systems

    Massimo Lumaca, Boris Kleber ... Giosue Baggio
    Resting-state functional connectivity between core regions of fronto-temporal auditory networks can distinguish music transmitters from innovators.
    1. Neuroscience

    Augmented reality powers a cognitive assistant for the blind

    Yang Liu, Noelle RB Stiles, Markus Meister
    A non-invasive cognitive assistant for blind people endows objects in the environment with voices, allowing users to explore the scene, localize objects, and navigate through a building with minimal training.