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The giant caiman Purussaurus from the Miocene of Venezuela is the first recorded member of crown Crocodylia having three sacrals, thus breaking the otherwise strict vertebral constraint of the group.

Subterranean fossil bone hosts a living microbiome different from the surrounding sediment without evidence of original protein preservation.

Disruption of disulfide bond formation sensitizes resistant Gram-negative bacteria expressing β-lactamases and mobile colistin resistance enzymes to currently available antibiotics.

In the Arabidopsis ovule primordium, germinal fate plasticity is coupled to the morphogenetic processes shaping the organ.

Modulation of cytoplasmic lipopolysaccharide levels sensitises bacteria to polymyxin antibiotics, revealing a novel combination therapeutic approach.

A robust procedure to purify mRNAs and their associated proteins identify CFB2 as the critical protein that binds and influences the fate of the main virulence factor in Trypanosoma brucei.

A crucial step during the mitophagy cascade involves the disassembly of connections between mitochondria and the endoplasmic reticulum via the retrotranslocation of Mfn2 tethering complexes by the Parkinson's disease genes PARKIN and PINK1, as well as the ATPase VCP/p97.

Encapsulin-associated ferritin proteins form metal-dependent decamers that are active as ferroxidase enzymes, but require encapsulation to form an iron store.

A novel molecular strategy to block transcription factor activity using small molecule interference of multiple protein-protein interactions is reported.

Phylogenomics of sea urchins clarifies their origins and diversification history, reveals surprising discrepancies with their rich fossil record, and serves as basis to explore the sensitivity of time calibration analysis.