William L Hamilton, Gerry Tonkin-Hill ... COVID-19 Genomics Consortium UK
SARS-CoV-2 can spread efficiently within care homes causing outbreaks among residents, who are at increased risk of severe disease, emphasising the importance of stringent infection control in this population.
Botond Antal, Liam P McMahon ... Lilianne R Mujica-Parodi
Patients with Type 2 diabetes show patterns of neurodegeneration consistent with accelerated brain aging, including impaired cognition and loss of brain volume, which are more severe in those with increased disease duration.
Seaho Kim, CheukMan C Au ... Paraskevi Giannakakou
Advanced microscopy techniques reveal unique biological features that distinguish androgen receptor variant 7 (AR-V7) from the canonical AR, including high intranuclear mobility and rapid nuclear import that occurs independently of importin-α/β.
Even moderate winds cause auks to abort landing attempts at nest-sites, and as a result, wind characteristics may affect where these, and other seabirds, choose to breed.
Heli Julkunen, Anna Cichońska ... Nightingale Health UK Biobank Initiative
Metabolic biomarkers measured from single blood test can identify apparently healthy people at high susceptibility for developing severe pneumonia, and may also be useful for preventive COVID-19 screening.
Manfred G Kitzbichler, Daniel Martins ... Neil A Harrison
Revealing two distinct brain systems linked to obesity, this research illuminates the intricate relationship between obesity, brain microstructure and genetics with potential implications for treatment and prevention.
The ASAP initiative promotes open and collaborative practices, and works with other foundations and projects in an effort to understand the mechanisms responsible for the onset and progression of Parkinson's.