406 results found
    1. Neuroscience

    Cerebellar associative sensory learning defects in five mouse autism models

    Alexander D Kloth et al.
    Five mouse models of autism show deficits in delay eyeblink conditioning, a form of split-second sensory learning that involves the cerebellum, a frequent site of disruption in autistic brains.
    1. Neuroscience

    Increased influence of prior choices on perceptual decisions in autism

    Helen Feigin et al.
    Perceptual decisions are influenced by preceding choices to a larger extent in individuals with autism spectrum disorder, such that they demonstrate a greater consistency bias.
    1. Neuroscience

    Default mode-visual network hypoconnectivity in an autism subtype with pronounced social visual engagement difficulties

    Michael V Lombardo et al.
    Functional hypoconnectivity between ‘social brain’ default mode circuitry and visual association cortex underpins a subtype of autistic toddlers with a strong preference to attend to the non-social visual world.
    1. Neuroscience
    2. Medicine

    Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

    Stavros Trakoshis et al.
    Excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic males versus females.
    1. Neuroscience

    Impaired voice processing in reward and salience circuits predicts social communication in children with autism

    Daniel Arthur Abrams et al.
    Children with autism often 'tune out' the voices in their environment and new results show that impaired processing of voices in the brain's reward system may underlie this social behavior.
    1. Neuroscience

    Perception in autism does not adhere to Weber’s law

    Bat-Sheva Hadad, Sivan Schwartz
    Perception in autism is sensitive to absolute rather than to relative metrics of the environment, encoding changes in the environment without calibrating the changes relative to reference stimulation.
    1. Neuroscience

    Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat

    Hala Harony-Nicolas et al.
    The production, validation and study of a novel rat model for Phelan McDermid Syndrome shows an ameliorative effect of oxytocin on both social and attentional deficits.
    1. Genetics and Genomics
    2. Neuroscience

    CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks

    Eric Deneault et al.
    Autism-associated iPSC-derived neurons mutant in CNTN5 or EHMT2 are hyperactive.
    1. Neuroscience

    Early alterations of social brain networks in young children with autism

    Holger Franz Sperdin et al.
    Toddlers with autism spectrum disorders have alterations in gaze patterns together with frequency specific network atypicalities between key brain areas of the social brain when freely exploring naturalistic and ecologically valid dynamic social stimuli.
    1. Epidemiology and Global Health

    Autism and attention-deficit/hyperactivity disorder among individuals with a family history of alcohol use disorders

    Jan Sundquist et al.
    A Swedish national cohort study reveals that children with a family history of alcohol use disorders have an increased risk of autism and attention-deficit/hyperactivity disorder.

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