In this episode we hear about using electrons for protein crystallography, a receptor for carbon dioxide, arthritis, how the brain responds to a missing hand, and the best shape for whiskers.
Of all the tools that Diana Ordonez used to study populations of immune cells during her PhD and postdoc research, flow cytometry was the most important. Now she uses her experience and skills to advise and support other researchers as a Flow Cytometrist at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany.
P2ry12-CreER robustly and specifically labels microglia in fate-mapping and ribosomal profiling experiments, revealing new markers for myeloid subpopulations in the central nervous system.
Potential for specific microbiome-directed, MHC-restricted shaping of a commonly selected HIV-specific CD8+ T cell population was suggested by MHC class I yeast display-based peptide screening approaches.