A common genomic deletion in various human cancers disrupts mitochondrial protein homeostasis in a way that might be targeted by existing drugs.

Cellular etiology of a human WASH complex mutation in mice reveals its specific roles in neuronal organelle trafficking and a surprising role in motor impairments.

Single-cell analysis of the chloroplast redox response to high light and oxidative stress revealed light-dependent heterogeneity, and was linked to cell fate determination within isogenic diatom populations.

scRNA-seq revealed the fish kidney is a dual-functional entity with functionalities of both primary and secondary lymphoid organs and highlighted the multifaced biology of kidney in ancient vertebrates.

SIT4 deletion and phosphate starvation increase mitochondrial membrane potential via electron transport chain dependent and independent manners, and the increased membrane potential induced by phosphate depletion is conserved between yeast, flies, and humans.

Selective transfer of mitochondria in the Balbiani body ensures high-quality oocyte mitochondria at extreme ploidy, explaining many enigmatic features of female germline architecture including germ cell loss.

Genetic analyses and biochemical studies show that JMJD6 promotes MYC-mediated transformation and is required for neuroblastoma growth by complexing with pre-mRNA splicing factors.