The system that controls gene expression by the plant signaling molecule auxin has deep evolutionary roots, and stepwise increases in system complexity shaped the highly diverse auxin response in land plants.

SWI/SNF chromatin remodeling complexes act as ‘gatekeepers’ for auxin responses and directly interact with the auxin response factor MONOPTEROS.

The auxin-sensitive Aux/IAA transcriptional repressors regulate approximately 35% of the annotated genes in Physcomitrella patens and exhibit complex interactions with both the activating and repressing ARF transcription factors.

E3 ubiquitin ligase Bre1-induced H2B monoubiquitination is epigenetically important for recruiting replication factor Mcm10 and cohesion establishment factors Ctf4, Ctf18 and Eco1 to early replication origins to establish sister chromatid cohesion.

Transcription factors that specify the identity of individual neuron types via activating terminal differentiation gene batteries also restrict cellular plasticity via altering the chromatin landscape.

Long-term hair follicle stem cells arise by embryonic progenitor cells occupying a niche location that is defined by attenuated Wnt/β-catenin signal.

Fluorescent sensors for the hormone abscisic acid have been developed using a high-throughput platform, and used to monitor hormone dynamics in plant roots and leaves.

Daple is a guanine nucleotide-exchange factor (GEF) for trimeric G proteins that enables Wnt/Frizzled receptors to transactivate G proteins during non-canonical Wnt signaling.