2,054 results found
    1. Neuroscience

    Dendritic coincidence detection in Purkinje neurons of awake mice

    Christopher J Roome, Bernd Kuhn
    Simultaneous voltage and calcium two-photon imaging of Purkinje neuron dendrites in awake mice reveals multiple interplaying mechanisms underlying sensory-evoked dendritic coincidence detection of parallel fiber and climbing fiber input.
    1. Neuroscience

    Irregular spiking of pyramidal neurons organizes as scale-invariant neuronal avalanches in the awake state

    Timothy Bellay et al.
    Spontaneous, irregular spiking in single cortical pyramidal neurons assembles as neuronal avalanches at the group level identifying a robust scale-invariant organization of resting activity in the awake state.
    1. Neuroscience

    State-dependent cell-type-specific membrane potential dynamics and unitary synaptic inputs in awake mice

    Aurélie Pala, Carl CH Petersen
    Membrane potential recordings in awake mice from two genetically defined classes of neocortical inhibitory neurons reveal their distinct patterns of activity and unitary excitatory synaptic inputs, which are differentially modulated by behavior and local network activity.
    1. Computational and Systems Biology
    2. Neuroscience

    Sub-minute prediction of brain temperature based on sleep–wake state in the mouse

    Yaniv Sela et al.
    The sleep–wake state sequence explains almost all of the variance in brain temperature in the mouse, and its detailed dynamics can be accurately predicted only using sleep–wake information.
    1. Neuroscience

    Mapping oxygen concentration in the awake mouse brain

    Declan G Lyons et al.
    Two-photon phosphorescence lifetime microscopy reveals the physiological values of oxygen concentration and blood flow parameters in the brains of awake mice.
    1. Neuroscience

    Gating of reafference in the external cuneate nucleus during self-generated movements in wake but not sleep

    Alexandre Tiriac, Mark S Blumberg
    A neural gating mechanism in the external cuneate nucleus of the rat brain is engaged during wake movements and disengaged during sleep-related twitches.
    1. Neuroscience

    Rai1 frees mice from the repression of active wake behaviors by light

    Shanaz Diessler et al.
    Halving dosage of the Smith-Magenis syndrome responsible gene Rai1 in the mouse greatly amplifies the direct, suppressing effects of light on active-wake behavior through increased activation of the ventral-subparaventricular zone.
    1. Neuroscience

    Propagated infra-slow intrinsic brain activity reorganizes across wake and slow wave sleep

    Anish Mitra et al.
    Human fMRI experiments reveal differences in the propagation of spontaneous brain activity during sleep versus wakefulness.
    1. Neuroscience

    Developmental 'awakening' of primary motor cortex to the sensory consequences of movement

    James C Dooley, Mark S Blumberg
    Early in development, before neurons in primary motor cortex are involved in motor control, they undergo a rapid transition in how they process sensory information following sleep and wake movements.
    1. Neuroscience

    Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle

    Heng Zhou et al.
    Dynamic calcium activity in the hippocampus changes markedly across behavioral and physiological states and depends on muscarinic acetylcholine receptor activation.

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