755 results found
    1. Neuroscience

    Neuroscience: How to train a neuron

    Rui P Costa, Alanna J Watt, P Jesper Sjöström
    Version of Record
    Insight
    1. Neuroscience

    Changing the responses of cortical neurons from sub- to suprathreshold using single spikes in vivo

    Verena Pawlak, David S Greenberg ... Jason ND Kerr
    Changing the order in which presynaptic and postsynaptic cells are repeatedly activated can change what a mammalian visual cortex neuron communicates to downstream neurons.
    1. Neuroscience
    2. Medicine

    Common resting brain dynamics indicate a possible mechanism underlying zolpidem response in severe brain injury

    Shawniqua T Williams, Mary M Conte ... Nicholas D Schiff
    The therapeutic effects of the sleeping pill zolpidem in patients with disorders of consciousness may be due to recruitment of brain cells idling in abnormally low-frequency brain waves.
    1. Neuroscience

    Decoding neural responses to temporal cues for sound localization

    Dan FM Goodman, Victor Benichoux, Romain Brette
    Computer simulations of interaural time difference decoders show that heterogeneous tuning of binaural neurons leads to accurate sound localization in natural environments.
    1. Neuroscience

    Development of schemas revealed by prior experience and NMDA receptor knock-out

    George Dragoi, Susumu Tonegawa
    Novel spatial representations by hippocampal cellular assemblies develop on the framework of preconfigured hippocampal networks whose homeostatic synaptic reorganization is accelerated by prior experience and CA3 NMDAR-dependent plasticity.
    1. Neuroscience

    Interaction of plasticity and circuit organization during the acquisition of cerebellum-dependent motor learning

    Yan Yang, Stephen G Lisberger
    During learning, one climbing fiber input instructs plasticity that is expressed in the simple-spike responses of cerebellar Purkinje cells, and causes neural learning that may inhibit future climbing fiber instructions.
    1. Neuroscience

    Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2

    Alexander M Herman, Longwen Huang ... Benjamin R Arenkiel
    Optogenetic techniques, whereby light is used to activate neuronal cells, are quickly becoming widely used in neuroscience; but excessive exposure to light can actually silence certain types of neuronal cells.
    1. Neuroscience

    Identification of Redeye, a new sleep-regulating protein whose expression is modulated by sleep amount

    Mi Shi, Zhifeng Yue ... Amita Sehgal
    A gene found in Drosophila, and named redeye, encodes a protein that accumulates during sleep deprivation and forms part of the homeostatic system that promotes and maintains sleep.
    1. Neuroscience

    Auditory synapses to song premotor neurons are gated off during vocalization in zebra finches

    Kosuke Hamaguchi, Katherine A Tschida ... Richard Mooney
    Intracellular recordings in singing birds and images of synapses in deafened birds provide insights into the neural circuitry that enables songbirds to fine-tune their songs.
    1. Neuroscience

    Long term functional plasticity of sensory inputs mediated by olfactory learning

    Nixon M Abraham, Roberto Vincis ... Alan Carleton
    Associative learning, but not passive odorant exposure, induces a novel long lasting functional plasticity in the periphery of mouse olfactory system, making previously encountered odors easier to detect in the future.

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