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    1. Neuroscience

    TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

    Christopher N Rudzitis, Monika Lakk ... David Križaj
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors

    Vincent Huson, Wade G Regehr
    Different glutamate receptors have specialized roles that allow cerebellar unipolar brush cells to transform realistic mossy fiber input patterns into a continuum of temporal responses.
    1. Genetics and Genomics

    Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila

    Xiaoyu Wu, Xingzhuo Yang ... Juan Du
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebrafish mutants of Alzheimer’s disease risk genes

    François Kroll, Joshua Donnelly ... Jason Rihel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    High-resolution awake mouse fMRI at 14 tesla

    David Hike, Xiaochen Liu ... Xin Yu
    High-resolution blood oxygen level-dependent functional magnetic resonance imaging enables brain-wide mapping of activated regions during sensory stimulation in awake mice, including associated areas, for high-order sensory processing including anticipation responses.
    1. Neuroscience

    Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans

    Rashi Pant, Kabilan Pitchaimuthu ... Brigitte Röder
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Real-Time Closed-Loop Feedback System For Mouse Mesoscale Cortical Signal And Movement Control: CLoPy

    Pankaj K Gupta, Timothy H Murphy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Quantification of the effect of hemodynamic occlusion in two-photon imaging

    Baba Yogesh, Matthias Heindorf ... Georg B Keller
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Evaluating hippocampal replay without a ground truth

    Masahiro Takigawa, Marta Huelin Gorriz ... Daniel Bendor
    A novel tool enables cross-checking the quality of replay events and evaluating the effectiveness of a given replay detection method in the absence of a ground truth.
    1. Neuroscience

    Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment

    Mengqiao Cui, Xiaoyuan Pan ... Jun-Li Cao
    RNA-Seq analysis and molecular biological approaches reveal a novel mechanism and provide a promising preventive and therapeutic molecular target for vulnerability to chronic pain-related memory impairment.
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