1,989 results found
    1. Developmental Biology

    Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish

    Brent W Bisgrove et al.
    Maternal Gdf3 and Nodal are interdependent obligatory cofactors in the fundamental patterning of the vertebrate embryonic axis of zebrafish.
    1. Developmental Biology

    Dynamic BMP signaling polarized by Toll patterns the dorsoventral axis in a hemimetabolous insect

    Lena Sachs et al.
    During the evolution of insect lineages, a signaling pathway dedicated to pathogen defense was co-opted for a new role in embryonic patterning.
    1. Developmental Biology

    A novel role for Ets4 in axis specification and cell migration in the spider Parasteatoda tepidariorum

    Matthias Pechmann et al.
    In the spider Parasteatoda tepidariorum the transcription factor Ets4 is needed for cumulus integrity, dorsoventral patterning and for the activation of hunchback and twist expression.
    1. Cell Biology
    2. Developmental Biology

    bicoid mRNA localises to the Drosophila oocyte anterior by random Dynein-mediated transport and anchoring

    Vítor Trovisco et al.
    The localisation of bicoid mRNA depends on its microtubule-independent anchoring at the oocyte anterior.
    1. Developmental Biology

    Patterning and Axis Formation: Heterodimers reign in the embryo

    Benjamin Tajer, Mary C Mullins
    Experiments by three independent groups on zebrafish have clarified the role of two signaling factors, Nodal and Gdf3, during the early stages of development.
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  1. Research: Publication bias and the canonization of false facts

    Silas Boye Nissen et al.
    Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.
  2. Tutorial: How to draw the line in biomedical research

    Lisa Huang et al.
    When analysing the data in a two-dimensional scatter plot, researchers should consider plotting the three regression lines that can be calculated for such a plot.
    1. Stem Cells and Regenerative Medicine

    Regeneration: Learning about loss

    Alejandro Sánchez Alvarado
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  3. Plain-language Summaries of Research: The value of a healthy relationship

    Bridget M Kuehn
    Biomedical science benefits when plain language allows patients to engage with all stages of the research process.

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