8,429 results found
    1. Epidemiology and Global Health

    A century of trends in adult human height

    NCD Risk Factor Collaboration (NCD-RisC)
    Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.
    1. Biochemistry and Chemical Biology

    Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function

    Susanne Gerndt, Cheng-Chang Chen ... Christian Grimm
    The lysosomal ion channel TPC2 emerges as an example of an ion channel in which ion selectivity is not fixed but rather agonist-selective.
    1. Computational and Systems Biology
    2. Neuroscience

    Interrogating theoretical models of neural computation with emergent property inference

    Sean R Bittner, Agostina Palmigiano ... John Cunningham
    Emergent property inference, a novel machine learning methodology, learns distributions of neural circuit model parameters that produce computational properties and provides novel scientific insight through the quantification of the rich parametric structure it captures.
    1. Physics of Living Systems

    Dynamics of immune memory and learning in bacterial communities

    Madeleine Bonsma-Fisher, Sidhartha Goyal
    Bacterial CRISPR immunity tracks phage mutations, creating immune diversity in bacterial populations that parallels phage genetic diversity and patterns of phage evolution that are determined by the type and degree of immune cross-reactivity in the CRISPR system.
    1. Neuroscience
    2. Computational and Systems Biology

    Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging

    Jessica A Haley, Tianyi Chen ... Sreekanth H Chalasani
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    • Incomplete
    1. Neuroscience

    Judging the difficulty of perceptual decisions

    Anne Löffler, Ariel Zylberberg ... Daniel M Wolpert
    Deciding which of two perceptual decisions is more difficult involves sequential sampling processes that terminate when the difference in accumulated evidence for each decision exceeds a threshold.
    1. Neuroscience

    The integrated brain network that controls respiration

    Friedrich Krohn, Manuele Novello ... Laurens WJ Bosman
    The primary rhythm generators controlling respiration are integrated in a much larger network of brain regions, including areas not typically considered to be respiratory control centers, and that allow respiration to be adapted to all forms of ongoing behavior.
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression

    Jie Lin, Yujian Wen ... Hao Zhu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Distractor effects in decision making are related to the individual’s style of integrating choice attributes

    Jing Jun Wong, Alessandro Bongioanni ... Bolton KH Chau
    Computational modelling reveals variations in people’s preferences towards integrating choice attributes using an additive or multiplicative approach, which affected whether the presence of valuable distractors facilitate or impair decision making.
    1. Neuroscience

    Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults

    Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete

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