2,101 results found
    1. Neuroscience

    Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner

    Kang-Ying Qian et al.
    Male pheromone environment increases the cholinergic synaptic transmission at the neuromuscular junction in Caenorhabditis elegans hermaphrodites during development, decreasing hermaphrodites' locomotion activity and promoting mating efficiency.
    1. Neuroscience

    IGF-1 facilitates extinction of conditioned fear

    Laura E Maglio et al.
    Insulin-like growth factor-1 activates the prefrontal cortex and improves the extinction of aversive memories.
    1. Ecology

    Relative demographic susceptibility does not explain the extinction chronology of Sahul’s megafauna

    Corey JA Bradshaw et al.
    There is no relationship between the demographic susceptibility to extinction and the estimated extinction chronology among Sahul’s megafauna, suggesting that human choices, a species’ ecological requirements, and/or random climate variation instead determined the extinction chronology.
    1. Developmental Biology
    2. Genetics and Genomics

    Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose

    Zhejun Ji et al.
    Cell competition is an important mechanism selecting against aneuploid cells.
    1. Cell Biology

    A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage

    Madhuja Samaddar et al.
    A whole-genome genetic screen links new aspects of oocyte maturation to proteostasis renewal in the immortal Caenorhabditis elegans germ-cell lineage and reveals similarities to somatic cell maintenance during aging.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Ancient DNA reveals the lost domestication history of South American camelids in Northern Chile and across the Andes

    Paloma Diaz-Maroto et al.
    aDNA revealed a model of domestication where an ancient guanaco population no longer exists, the loss of the ancient vicuña genetic variation in the modern populations, and frequently interbreeding practices.
    1. Neuroscience

    Acquisition of innate odor preference depends on spontaneous and experiential activities during critical period

    Qiang Qiu et al.
    A delicate balance of neural activity is required during critical period in establishing innate odor preference.
    1. Computational and Systems Biology
    2. Medicine

    Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial

    Dimitrios Chantzichristos et al.
    A human experimental model for physiological glucocorticoid exposure and glucocorticoid withdrawal identifies a multi-omic cluster, including microRNA miR-122-5p and metabolites, associated with glucocorticoid-responsive genes.
    1. Computational and Systems Biology
    2. Developmental Biology

    Single-cell transcriptomics of the Drosophila wing disc reveals instructive epithelium-to-myoblast interactions

    Nicholas J Everetts et al.
    A single-cell atlas of the developing Drosophila wing disc at two time points enables a detailed understanding of the signals exchanged between different cell populations during development.
    1. Developmental Biology

    Three-dimensional reconstruction of a whole insect reveals its phloem sap-sucking mechanism at nano-resolution

    Xin-Qiu Wang et al.
    3D reconstruction for an insect provides new internal structures at nanometer resolution, and the reconstructed feeding insect reveals unexpected contraction of stylet protractors and suggested a novel phloem sap-sucking model.

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