1,074 results found
    1. Neuroscience

    Control of voluntary and optogenetically perturbed locomotion by spike rate and timing of neurons of the mouse cerebellar nuclei

    Rashmi Sarnaik, Indira M Raman
    Stride-related modulated firing by neurons of the cerebellar nuclei is required for smooth execution of practiced locomotion and persists more easily with synchronous than asynchronous Purkinje-mediated inhibition.
    1. Neuroscience

    Postsynaptic plasticity of cholinergic synapses underlies the induction and expression of appetitive and familiarity memories in Drosophila

    Carlotta Pribbenow, Yi-chun Chen ... David Owald
    Specific memories can be stored through changes in the postsynaptic cholinergic receptor composition at Drosophila mushroom body synapses.
    1. Computational and Systems Biology
    2. Neuroscience

    Principles for coding associative memories in a compact neural network

    Christian Pritz, Eyal Itskovits ... Alon Zaslaver
    A compact neural network can form various associative memories that are encoded in a distributed manner, where each neuron stores different components of the memory.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Kinesin-4 KIF21B is a potent microtubule pausing factor

    Wilhelmina E van Riel, Ankit Rai ... Anna Akhmanova
    Kinesin-4 KIF21B combines a processive motor activity with two non-motor microtubule-binding domains and an autoregulatory region to induce pausing of microtubule plus ends.
    1. Neuroscience

    Parallel processing of quickly and slowly mobilized reserve vesicles in hippocampal synapses

    Juan Jose Rodriguez Gotor, Kashif Mahfooz ... John F Wesseling
    Reevaluation of reserve synaptic vesicle pools supports a new model of presynaptic function.
    1. Neuroscience

    Nutritional state-dependent modulation of insulin-producing cells in Drosophila

    Rituja S Bisen, Fathima Mukthar Iqbal ... Jan M Ache
    An in vivo electrophysiology approach identifies an incretin-like effect in Drosophila insulin-producing cells, highlighting key circuit dynamics which govern glucose homeostasis via conserved mechanisms.
    1. Neuroscience

    A neural circuit for gamma-band coherence across the retinotopic map in mouse visual cortex

    Richard Hakim, Kiarash Shamardani, Hillel Adesnik
    A neural circuit between layer 2/3 pyramidal cells and somatostatin-expressing inhibitory neurons synchronizes spatially separated regions of the visual cortex to gamma rhythms.
    1. Neuroscience

    Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila

    Katharina Eichler, Stefanie Hampel ... Andrew M Seeds
    A synaptic resolution somatotopic map of nearly all mechanosensory neurons on the Drosophila head that individually elicit aimed grooming of specific head locations and collectively elicit a head grooming sequence.
    1. Neuroscience

    The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion

    Lian Hollander-Cohen, Omer Cohen ... Berta Levavi-Sivan
    Genetic loss-of-function approaches and functional calcium imaging reveal cholecystokinin as the primary regulator of follicle-stimulating hormone in zebrafish, redefining our understanding of gonadotropin regulation in vertebrates.
    1. Neuroscience

    Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal sensitive period

    Sarah E Canetta, Emma S Holt ... Christoph Kellendonk
    Prefrontal PV interneuron activity during development is necessary for prefrontal circuit maturation, supporting adult prefrontal network function and cognitive flexibility.

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