546 results found
    1. Neuroscience

    Memory recall involves a transient break in excitatory-inhibitory balance

    Renée S Koolschijn et al.
    Hippocampal activity during memory recall predicts a transient increase in the ratio between neocortical glutamate and GABA, thereby allowing otherwise dormant memories to be released.
    1. Developmental Biology
    2. Neuroscience

    Activity-dependent modulation of synapse-regulating genes in astrocytes

    Isabella Farhy-Tselnicker et al.
    RNA sequencing and genetic mouse models reveal that transcriptional changes to astrocytes in the developing cortex are not intrinsic but influenced by their environment and determine that expression of astrocyte synapse-regulating genes and neuronal synaptogenesis is modulated by ongoing astrocyte-neuron communication.
    1. Neuroscience

    Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for neural repair

    Oshri Avraham et al.
    The microenvironment surrounding sensory neurons in dorsal root ganglia responds differently to peripheral and central injuries, revealing that non-neuronal cells can be manipulated to promote axon regeneration after central injury.
    1. Immunology and Inflammation

    Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes

    Alejandro J Brenes et al.
    In-depth proteomic analyses of intestinal tissue-resident intraepithelial T lymphocytes reveals how these cells are adapted to the intestinal environment through increased cholesterol and lipid metabolism, tailored metabolic profiles, receptors for interacting with epithelial cells, and tightly regulated signalling pathways.
    1. Biochemistry and Chemical Biology

    A universal pocket in fatty acyl-AMP ligases ensures redirection of fatty acid pool away from coenzyme A-based activation

    Gajanan S Patil et al.
    The structural basis of how an enzyme differentiates chemically identical molecules unlike its homolog to channel fatty acids towards secondary metabolism is elucidated.
    1. Neuroscience

    Dorsal premammillary projection to periaqueductal gray controls escape vigor from innate and conditioned threats

    Weisheng Wang et al.
    Activity in the hypothalamic dorsal premammillary nucleus predicts future escape from threat, represents escape velocity, and controls escape velocity via a projection to the brainstem.
    1. Neuroscience

    A quadratic model captures the human V1 response to variations in chromatic direction and contrast

    Michael A Barnett et al.
    A quantitative forward model captures fMRI responses to chromatic stimuli in human primary visual cortex and quantifies how chromatic sensitivity changes with eccentricity.
    1. Neuroscience

    Developmental change in prefrontal cortex recruitment supports the emergence of value-guided memory

    Kate Nussenbaum, Catherine A Hartley
    The use of prior experience to adaptively prioritize information in memory increases from childhood to adulthood and engages corticostriatal circuitry.
    1. Developmental Biology
    2. Neuroscience

    Spinal lumbar dI2 interneurons contribute to stability of bipedal stepping

    Baruch Haimson et al.
    Spinal dI2 interneurons relay peripheral and intraspinal feedback to premotor networks in the spinal cord and the cerebellum to ensure the stability of bipedal stepping.
    1. Neuroscience

    Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain

    Gabriella R Sterne et al.
    A split-GAL4 collection provides precise genetic targeting of 138 neuronal cell types in the subesophageal zone of adult Drosophila melanogaster.

Refine your results by:

Type
Research categories