Individual granule cells within the cerebellum-the region of the brain that coordinates movement and supports the learning of new motor skills-receive both sensory and motor input streams: an arrangement that may help the brain to use feedback to fine-tune movement.

The Notch signaling pathway has a central role in the development of the nervous system, and also in the establishment of networks of connections in the adult brain

The Notch signaling pathway has a central role in the formation of the circuit that controls egg-laying in the nematode worm C. elegans.

Membrane receptor proteins move through primary cilia largely by passive diffusion rather than by active intraflagellar transport.

Skin cells from a patient with retinitis pigmentosa have been used to generate induced pluripotent stem cells, which could potentially form the basis of new treatments for this disease.

A protein called Megf8 regulates the activity of key signaling molecules involved in the development of the peripheral nervous system.

The signaling molecule Frizzled3 plays a part in the development of the nervous system by controlling the ability of motor neurons to form connections with distant target muscles.

The delayed-onset of asynchronous transmitter release seen in neurons that fire repeatedly is triggered by a different source of calcium from that which triggers synchronous transmitter release.

PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.

Computer simulations show that the firing patterns of branched touch receptors can be set in part by the organization of their sensory endings in the skin.