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    1. Neuroscience

    Hierarchy between forelimb premotor and primary motor cortices and its manifestation in their firing patterns

    Akiko Saiki-Ishikawa, Mark Agrios ... Andrew Miri
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Natural ITD statistics predict human auditory spatial perception

    Rodrigo Pavão, Elyse S Sussman ... José L Peña
    Human brain has incorporated natural statistics of spatial cues to the neural code supporting perception of sound location.
    1. Neuroscience

    Principal cells of the brainstem’s interaural sound level detector are temporal differentiators rather than integrators

    Tom P Franken, Philip X Joris, Philip H Smith
    Principal neurons of the brainstem nucleus comparing sound level at the two ears do not have the slow response properties previously attributed to them, but are instead specialized for fast weighing of excitation and inhibition.
    1. Neuroscience

    NaV1.1 is essential for proprioceptive signaling and motor behaviors

    Cyrrus M Espino, Cheyanne M Lewis ... Theanne N Griffith
    The voltage-gated sodium channel Nav1.1 is identified as an essential component of the proprioceptive transmission machinery that is required in vivo for normal motor behavior.
    1. Evolutionary Biology
    2. Neuroscience

    Neuro-evolutionary evidence for a universal fractal primate brain shape

    Yujiang Wang, Karoline Leiberg ... Bruno Mota
    Cortices from 11 primate species share the same archetypal fractal shape, indicating a universal mechanism for primate and mammalian cortical folding, and suggesting novel shape biomarkers for brains.
    1. Developmental Biology

    Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification

    Heejin Nam, Shin Jeon ... Seunghee Lee
    Shh, produced by postmitotic spinal neurons, plays crucial roles in the specification of the lateral motor column of the spinal cord through ARHGAP36.
    1. Cell Biology
    2. Developmental Biology

    Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

    Sun-Hee Hwang, Bandarigoda N Somatilaka ... Saikat Mukhopadhyay
    Signaling specifically in cilia by a cAMP generating G-protein-coupled receptor directs tissue-specific morphogenesis.
    1. Neuroscience

    The effects of chloride dynamics on substantia nigra pars reticulata responses to pallidal and striatal inputs

    Ryan S Phillips, Ian Rosner ... Jonathan E Rubin
    The effects of chloride homeostasis can explain diverse responses of basal ganglia output neurons to putatively inhibitory inputs and may tune these neurons' synchrony, oscillations and behavior in decision-making scenarios.
    1. Neuroscience

    Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway

    Artemis Koumoundourou, Märt Rannap ... Stefan Britsch
    Molecular genetic, cell culture as well as electrophysiological analyses reveal a C1ql2/Neurexin3(25b+)-dependent molecular pathway through which Bcl11b controls critical functions of adult hippocampal mossy fiber synapses.
    1. Neuroscience

    The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2

    Pierre-Louis Ruffault, Fabien D'Autréaux ... Christo Goridis
    The location of neurons responsible for increasing the breathing rate upon detecting elevated levels of CO2 in the blood has been pinpointed to the retrotrapezoid nucleus in the brainstem.