206 results found
    1. Computational and Systems Biology
    2. Physics of Living Systems

    A simple regulatory architecture allows learning the statistical structure of a changing environment

    Stefan Landmann et al.
    Minimal modifications of common regulatory circuits can allow bacteria to learn from the past to better predict the future, on a physiological, rather than evolutionary, timescale.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Characterization of the ABC methionine transporter from Neisseria meningitidis reveals that lipidated MetQ is required for interaction

    Naima G Sharaf et al.
    NmMetQ is a lipoprotein that tethers to membranes via a lipid anchor and has dual function and localization, playing a role in NmMetNI-mediated transport at the inner membrane and moonlighting on the bacterial surface.
    1. Cell Biology
    2. Developmental Biology

    Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans

    Mor Levi-Ferber et al.
    Neuronal circuits can be disrupted by ire-1-dependent mRNA decay to affect germline tumor cell identity by regulating cross-tissue communication in Caenorhabditis elegans.
    1. Developmental Biology
    2. Physics of Living Systems

    Rolling controls sperm navigation in response to the dynamic rheological properties of the environment

    Meisam Zaferani et al.
    Rheological properties of the environment regulate sperm swimming and navigational behavior through suppression or reactivation of sperm rolling around its longitudinal axis.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Olivier Cochet-Escartin et al.
    Cell assemblies can use environmental cues created by their own respiration, such as oxygen gradients, to collectively guide themselves to more favorable locations in a remarkably robust and long-lasting way.
    1. Cell Biology
    2. Developmental Biology

    GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility

    Sequoyah Reynoso et al.
    Spermatozoa require GIV for specialized compartmentalized signaling to support efficient capacitation while inhibiting premature acrosome reaction.
    1. Biochemistry and Chemical Biology

    Tissue-specific targeting of DNA nanodevices in a multicellular living organism

    Kasturi Chakraborty et al.
    DNA nanodevices can be targeted to specific cell types in Caenorhabditis elegans with subcellular precision by exploiting either endogenous or synthetic receptors.
    1. Neuroscience

    Resonating neurons stabilize heterogeneous grid-cell networks

    Divyansh Mittal, Rishikesh Narayanan
    Intrinsic neuronal resonance stabilizes heterogeneous neural networks by suppressing low-frequency perturbations.
    1. Ecology

    Inversion of pheromone preference optimizes foraging in C. elegans

    Martina Dal Bello et al.
    Worms' attraction to pheromones turns into repulsion when a food patch is depleted, helping them avoid already exploited territories and search for new food sources.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    High-speed, three-dimensional imaging reveals chemotactic behaviour specific to human-infective Leishmania parasites

    Rachel C Findlay et al.
    High-speed holographic microscopy shows that Leishmania parasites modify their swimming behaviour to target human macrophages.

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