Legionella pneumophila can be inhibited by its own antimicrobial, HGA (homogentisic acid), but its density-dependent resistance to HGA restricts the potential for self-harm.
Thibaud Taillefumier, Anna Posfai ... Ned S Wingreen
In a consumer-resource model obeying the physical requirement of flux conservation, metabolic competition between microbes yields consortia of cell types that collectively resist invasion via optimal use of resources.
Local abnormal fungi in Caesarean section scar diverticulum can affect the abundance of bacteria through specific metabolites, thereby destroying the stability of bacteria and the entire microbial community.
Both within and between hosts, the key factor guiding whether increasing treatment strength will increase or decrease antibiotic resistance is whether inter-strain competition is effective, not whether it is present.
Amichai Baichman-Kass, Tingting Song, Jonathan Friedman
High-throughput measurements of simplified bacterial communities find that when multiple species jointly inhibit a focal species of interest, their individual effects do not add up, but are dominated by the strongest single-species effect.
Elizabeth A Landis, Angela M Oliverio ... Benjamin E Wolfe
In the most comprehensive survey of sourdough starter biodiversity, this work identifies processes that control the diversity and function of sourdough microbiomes at a continental scale.
Jason A Metcalf, Lisa J Funkhouser-Jones ... Seth R Bordenstein
Parallel horizontal gene transfer has spread a bacteriolytic gene family to all domains of life, and has bestowed a niche-transcending adaptation in recipients that must deploy antibacterial molecules to survive in a bacterial world.