545 results found
    1. Cell Biology
    2. Physics of Living Systems

    A physical mechanism of TANGO1-mediated bulky cargo export

    Ishier Raote et al.
    TANGO1 functions as a linactant filament to stabilize shallow COPII-coated buds, and after which membrane tension regulation, possibly mediated by TANGO1-controlled membrane fusion, facilitates bud elongation for procollagen export.
    1. Cell Biology

    BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

    Chang Zhang et al.
    BLOS1 is a new regulator of LDLR endosomal recycling through coordinating kinesins during long-range transport, and depletion of BLOS1 in mouse liver leads to aberrant lipid metabolism.
    1. Cell Biology
    2. Developmental Biology

    Zebrafish Posterior Lateral Line primordium migration requires interactions between a superficial sheath of motile cells and the skin

    Damian E Dalle Nogare et al.
    Epithelial cells utilize a covering sheath of motile cells to migrate in confinement.
    1. Biochemistry and Chemical Biology

    Talin-activated vinculin interacts with branched actin networks to initiate bundles

    Rajaa Boujemaa-Paterski et al.
    At adhesion sites, talin-activated vinculin promotes interactions with the actin network that initiates bundles.
    1. Developmental Biology

    Asymmetric neurogenic commitment of retinal progenitors involves Notch through the endocytic pathway

    Elisa Nerli et al.
    A quantitative live imaging approach unveils that earliest neurogenic progenitors in the vertebrate retina arise from asymmetric divisions and that this asymmetry involves Notch signalling through the endocytic pathway.
    1. Cell Biology
    2. Immunology and Inflammation

    Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells

    Elizabeth Rivers et al.
    WASp is an immunometabolic regulator of human myeloid cells and regulates autophagy and mitochondrial homeostasis.
    1. Cell Biology

    A novel checkpoint pathway controls actomyosin ring constriction trigger in fission yeast

    Tomás Edreira et al.
    In fission yeast cell wall stress triggers a cytokinesis blockage specifically in the onset of actomyosin ring constriction.
    1. Cell Biology
    2. Developmental Biology

    Coordinated crosstalk between microtubules and actin by a spectraplakin regulates lumen formation and branching

    Delia Ricolo, Sofia J Araujo
    Lumen formation by single epithelial cells depends on FGF-signalling-dependent expression of a spectraplakin, which can be functionally replaced by Tau.
    1. Cell Biology
    2. Developmental Biology

    circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation

    Anne Kruse Hollensen et al.
    A neuron-specific circular RNA keeps neuronal differentiation in check by lowering transcription rates from key neuronal marker genes.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Evolution of multicellularity by collective integration of spatial information

    Enrico Sandro Colizzi et al.
    Selection for undifferentiated multicellularity emerges in an evolutionary cell-based model because a collective of cells performs chemotaxis better than single cells in a noisy environment.

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