215 results found
    1. Microbiology and Infectious Disease

    A dynamic bactofilin cytoskeleton cooperates with an M23 endopeptidase to control bacterial morphogenesis

    Sebastian Pöhl, Manuel Osorio-Valeriano ... Martin Thanbichler
    Analyses of the stalked budding bacterium Hyphomonas neptunium and its spiral-shaped relative Rhodospirillum rubrum reveal a conserved morphogenetic module that controls the establishment of complex bacterial cell shapes.
    1. Physics of Living Systems

    Mechanical instability and interfacial energy drive biofilm morphogenesis

    Jing Yan, Chenyi Fei ... Bonnie L Bassler
    Mechanical instabilities are shown to underlie the development of bacterial biofilm morphology, suggesting an ancient origin for mechano-morphogenesis, which is known to drive developmental processes in tissues in higher organisms.
    1. Cell Biology

    A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals

    Rosanna A Alegado, Laura W Brown ... Nicole King
    The development of colonies of cells in choanoflagellates, water-dwelling organisms that feed on bacteria, is triggered by the presence of very low concentrations of a lipid molecule produced by certain types of bacteria.
    1. Developmental Biology
    2. Evolutionary Biology

    Architecture and evolution of the cis-regulatory system of the echinoderm kirrelL gene

    Jian Ming Khor, Charles A Ettensohn
    The transcriptional control system of a sea urchin gene reveals the deep evolutionary conservation of a gene regulatory network underlying morphogenesis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A model symbiosis reveals a role for sheathed-flagellum rotation in the release of immunogenic lipopolysaccharide

    Caitlin A Brennan, Jason R Hunt ... Edward G Ruby
    Both beneficial and pathogenic bacteria can use their sheathed flagella during host colonization as a novel toxin-/signal-delivery mechanism.
    1. Cell Biology
    2. Developmental Biology

    Flattop regulates basal body docking and positioning in mono- and multiciliated cells

    Moritz Gegg, Anika Böttcher ... Heiko Lickert
    In cell types that acquire planar cell polarity, the protein Flattop regulates basal body docking and positioning.
    1. Cell Biology
    2. Developmental Biology

    FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis

    Melissa Kelley, John Yochem ... David S Fay
    A fibrillin-related protein, FBN-1, is a key component of the apical extracellular matrix and prevents epidermal cell deformation by biomechanical forces during morphogenesis of the C. elegans embryo.
    1. Cell Biology
    2. Developmental Biology

    Keratins and plakin family cytolinker proteins control the length of epithelial microridge protrusions

    Yasuko Inaba, Vasudha Chauhan ... Alvaro Sagasti
    Although intermediate filaments are not widely known to contribute to the morphogenesis of cellular protusions, keratin filaments and cytolinkers are critical for the development of microridge protrusions in zebrafish skin.
    1. Cell Biology
    2. Genetics and Genomics

    NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling

    Malini Rajan, Cole P Anderson ... Elizabeth A Leibold
    Nuclear receptor NHR-14 regulates the subcellular localization of the zinc transcription factor PQM-1 to coordinate innate immunity with iron sequestration during pathogen infection in C. elegans..

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