Staphylococcus aureus NAD kinase promotes infection by protecting bacteria from host antimicrobial defenses and by supporting production of major virulence factors.

Combination of stem cell engineering and CRISPR technologies created a facile method to genetically manipulate macrophages, a multifunctional cell type that plays critical roles in immunity, cancer, and tissue homeostasis.

The bacterial pathogen Listeria monocytogenes requires respiration for the maintenance of cellular redox homeostasis.

Enterococci faecium encodes unique peptidoglycan composition and remodeling activity that activates host immunity.

Listeria monocytogenes uses respiration to sustain a risky fermentative lifestyle during infection.

Unveiling the intricate web of interactions between G4 structures and pathogenicity islands in 89 bacterial genomes significantly advances our understanding of bacterial virulence mechanisms.

Bacteria release ATP as part of their attack in sepsis.

M. tuberculosis, the bacterium that causes the disease tuberculosis, uses a signaling system that senses multiple products of the host's immune system to modify gene expression to colonize the lung.

Functional characterization of a pair of cis-encoded antisense RNAs reveals a role for RNase III and antisense regulation in the biogenesis and regulatory activity of a bacterial virulence factor-regulating small RNA.

Receptor recognition of antimicrobial peptides is important for Salmonellae to survive inside macrophages and cause disease.