744 results found
    1. Ecology

    Dynamic metabolic exchange governs a marine algal-bacterial interaction

    Einat Segev, Thomas P Wyche ... Roberto Kolter
    Physical and chemical interactions with bacteria influence the life and death of Emiliania huxleyi, a bloom-forming micro-alga important in global biogeochemical cycles.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth

    Vivek V Thacker, Neeraj Dhar ... John D McKinney
    Time-lapse imaging and the modular recreation of host physiology reveal that alveolar epithelial cells, potential permissive infection sites for Mycobacterium tuberculosis, can restrict early bacterial growth via surfactant secretion.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    An elusive electron shuttle from a facultative anaerobe

    Emily Mevers, Lin Su ... Jon Clardy
    The identification of ACNQ as an extracellular electron shuttle solves a longstanding problem in bacterial physiology and provides new tool for bioenergy development.
    1. Evolutionary Biology

    The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts

    Patric M Vaelli, Kevin R Theis ... Heather L Eisthen
    Skin-associated bacteria underlie the production of a potent defensive neurotoxin in newts, impacting host physiology, molecular evolution, and predator-prey interactions in a coevolutionary arms race.
    1. Computational and Systems Biology

    Resource allocation accounts for the large variability of rate-yield phenotypes across bacterial strains

    Valentina Baldazzi, Delphine Ropers ... Hidde de Jong
    A coarse-grained model of microbial growth coupling fluxes of carbon and energy shows that resource allocation is a major explanatory factor of the observed variability of growth rates and growth yields across different bacterial strains.
    1. Physics of Living Systems

    Speed variations of bacterial replisomes

    Deepak Bhat, Samuel Hauf ... Simone Pigolotti
    The speed of replisomes in Escherichia coli depends on temperature and varies along the genome in a wave-like manner, with implications for bacterial physiology.
    1. Microbiology and Infectious Disease

    Gut microbiota density influences host physiology and is shaped by host and microbial factors

    Eduardo J Contijoch, Graham J Britton ... Jeremiah J Faith
    The density of the gut microbiota influences the host immune system and adiposity, and can be therapeutically manipulated.
    1. Biochemistry and Chemical Biology

    Post-translational flavinylation is associated with diverse extracytosolic redox functionalities throughout bacterial life

    Raphaël Méheust, Shuo Huang ... Samuel H Light
    Bioinformatic and biochemical studies provide evidence that covalently bound flavins are common and participate in wide-ranging extracytosolic redox activities throughout bacterial life.
    1. Microbiology and Infectious Disease

    Tools and methods for high-throughput single-cell imaging with the mother machine

    Ryan Thiermann, Michael Sandler ... Suckjoon Jun
    A user-friendly pipeline for analysis of time-lapse imaging data from the microfluidic mother machine.
    1. Ecology
    2. Microbiology and Infectious Disease

    Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance

    Andrés Aranda-Díaz, Benjamin Obadia ... Kerwyn Casey Huang
    Shifts in pH that result from metabolic interactions between members of the Drosophila gut microbiota were sufficient to modulate Lactobacillus plantarum tolerance to the antibiotics rifampin and erythromycin.

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