A peroxidase-containing nanocompartment in the bacterial pathogen Mycobacterium tuberculosis protects against oxidative stress and antibiotic treatment in the host.
The universal bacteria cell wall component peptidoglycan impacts the egg-laying behavior of infected Drosophila females by directly modulating the activity of few brain octopaminergic neurons.
Alexandre Giraud-Gatineau, Juan Manuel Coya ... Ludovic Tailleux
The anti-tuberculosis drug bedaquiline reprograms human macrophages into potent bactericidal phagocytes, which are able to control bacterial infection.
The growth of multicellular bacterial structures called biofilms generates forces that deform soft material substrates and disrupt epithelial cell layers, potentially mechanically damaging host tissue.
A systematical study of pslG mutants at both a single cell and community level reveals the importance of intracellular glycosyl hydrolase PslG on the cell fate and biofilm development of P. aeruginosa, an opportunistic pathogen that can cause persistent infections.
Samuel J Modlin, Derek Conkle-Gutierrez ... Faramarz Valafar
Fully assembled DNA methylomes from phylogeographically diverse clinical Mycobacterium tuberculosis complex isolates reveals 'intercellular mosaic methylation' as a source of epigenetic diversity.
A novel theory demonstrates how variation in the thermal responses of microbial populations can alter coexistance and thus explain patterns of richness across thermal gradients.
With the removal of confounding artifacts, ribosome profiling can yield insight into the mechanism of protein synthesis in bacteria at high resolution.
