The deletion of a single gene encoding a selective bile salt hydrolase from the abundant human gut bacterium Bacteroides thetaiotaomicron significantly alters host metabolism.
The development of colonies of cells in choanoflagellates, water-dwelling organisms that feed on bacteria, is triggered by the presence of very low concentrations of a lipid molecule produced by certain types of bacteria.
Time-lapse imaging and the modular recreation of host physiology reveal that alveolar epithelial cells, potential permissive infection sites for Mycobacterium tuberculosis, can restrict early bacterial growth via surfactant secretion.
A model of early postnatal bacterial meningitis in the mouse demonstrates the transcriptome responses of each of the major meningeal cell types and should prove useful in dissecting the pathophysiology of bacterial meningitis in human infants.
This time-shortened work flow improves sensitivity and specificity for the identification of bacteria in bone infections independently of bacterial culturability.
Jean-Baptiste Raina, Peta L Clode ... David G Bourne
The intracellular location of a key sulfur compound, dimethylsulfoniopropionate, was identified in microalgae and its subsequent uptake by marine bacteria was quantified using a combination of secondary-ion mass-spectrometry techniques.
Bioinformatic and biochemical studies provide evidence that covalently bound flavins are common and participate in wide-ranging extracytosolic redox activities throughout bacterial life.
A screen of lactic acid bacteria reveals that diet modulates the age-dependent decline of thermotaxis behavior in C. elegans without changing the organismal lifespan.
