131 results found
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome

    An Van den Bossche et al.
    A bacteriophage remodels the RNA metabolism machinery of a bacterial host to sequentially clear host transcripts and then stabilize the viral RNA.
    1. Microbiology and Infectious Disease

    Cell cycle constraints on capsulation and bacteriophage susceptibility

    Silvia Ardissone et al.
    A multi-layered and conserved cell cycle mechanism prevents capsulation, long known as a bacterial virulence determinant, in G1-phase and concurrently licenses bacteriophage-mediated genetic exchange prior to entry into S-phase.
    1. Cell Biology

    A bacteriophage tubulin harnesses dynamic instability to center DNA in infected cells

    Marcella L Erb et al.
    A bacteriophage tubulin homolog, PhuZ, forms a structure with the biochemical, structural, and functional properties of a simplified, bipolar spindle.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A bacteriophage endolysin that eliminates intracellular streptococci

    Yang Shen et al.
    Unlike other similar enzymes, the antimicrobial enzyme PlyC can interact with and translocate eukaryotic membranes, and then lyse and kill intracellular bacteria.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 Å resolution

    Xing Zhang et al.
    Cryo electron microscopy and structure-based mutagenesis reveal that the bacteriophage BPP-1 contains two of the three major recognized viral folds, one of which exhibits a new topology.
    1. Microbiology and Infectious Disease

    Research: A comprehensive and quantitative exploration of thousands of viral genomes

    Gita Mahmoudabadi, Rob Phillips
    A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.
    1. Microbiology and Infectious Disease

    Phage Predation: Killing the killers

    Marianne De Paepe, Marie-Agnès Petit
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