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    1. Neuroscience

    Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex

    B Semihcan Sermet et al.
    Two distinct thalamocortical pathways were found to provide differential excitatory synaptic input to distinct cell-types across layers of mouse primary somatosensory barrel cortex.
    1. Developmental Biology

    Longevity is impacted by growth hormone action during early postnatal period

    Liou Y Sun et al.
    Transient hormonal alterations during early critical developmental periods can have a crucial and long-lasting effect on lifespan in mice.
    1. Neuroscience

    Long-term consequences of the absence of leptin signaling in early life

    Angela M Ramos-Lobo et al.
    A mouse model that grew without functional leptin receptors until adulthood reveals that early defects in leptin signaling lead to permanent metabolic and developmental problems.
    1. Evolutionary Biology
    2. Plant Biology

    Evolution of herbivore-induced early defense signaling was shaped by genome-wide duplications in Nicotiana

    Wenwu Zhou et al.
    Comparative transcriptomic analysis reveals the molecular basis and evolution of herbivore-associated early defense signaling in Nicotiana.
    1. Microbiology and Infectious Disease

    A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane

    Anna Konovalova et al.
    Mutations that block assembly of the interlocked RcsF/β barrel protein complex prevent detection of lipopolysaccharide stress and activation of Rcs signal transduction pathway.
  1. Ben Barres Spotlight Awards: Applications open for 2020

    Applications are now open for this year’s Ben Barres Spotlight Awards, offering scientists from minoritized groups up to $6,000 each to use to advance their research career.
  2. Privacy Notice: Ben Barres Spotlight Awards

    Details related to the data held and processed as part of applications to the Ben Barres Spotlight Awards.
  3. Ben Barres: In memory of a remarkable colleague

    eLife editors share a short tribute to Ben Barres: neuroscientist, former eLife Reviewing Editor, and advocate for young scientists, women, and scientists of diverse backgrounds.
    1. Cancer Biology
    2. Genetics and Genomics

    Tumor Evolution: Finding the mutations that drive resistance

    Nadine Bley
    Mutations that allow tumors to evolve and become resistant to treatment can be readily identified with a new sequencing approach.
    Insight
    Available as:
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  4. Research Communication: Ways to increase equity, diversity and inclusion

    Devang Mehta et al.
    ​​ The eLife Early-Career Advisory Group calls for radical changes at eLife and other journals to make science more diverse and inclusive.
    Editorial
    Available as:
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