Multimegadalton intraflagellar transport (IFT) trains assemble by sequential recruitment of IFT subcomplexes from the cell body to the ciliary basal bodies and tubulin, the main IFT cargo, is loaded briefly before trains depart.

At optimal concentrations, the ciliary inhibitor Cp110 promotes ciliogenesis by localization to previously uncharacterized sites at the basal body, where it recruits ciliary adhesion complexes that mediate basal body interaction with F-actin networks.

Mutations in KIAA0586 (TALPID3) cause a severe ciliopathy called Joubert syndrome that affects organ, cell and centrosome polarity.

In cell types that acquire planar cell polarity, the protein Flattop regulates basal body docking and positioning.

The numerous reports in support of action-value representation in the striatum are based on statistical analyses that are subject to two critical confounds and, thus, this long-held belief of striatal action-value representation should be retested using different experiments and analyses.

Cdk5-mediated stabilization of Acinus in postmitotic neurons promotes autophagy and the removal of protein aggregates linked to neurodegeneration in Drosophila melanogaster.

The basal body of the type-III secretion system of Yersinia enterocolitica within bacterial membranes shows elasticity and is longer than related isolated systems.

Centriolar satellites facilitate efficient trafficking of proteins to and from centrioles and are required for early steps of cilia formation and timely ciliogenesis in vivo, where mice lacking satellites display perinatal lethality, hydrocephalus, oligospermia, and cerebellar hypoplasia.

A detailed description of the structure of procentriole MT triplet by cryoET, along with its associated non-tubulin proteins and its assembly intermediates, reveals possible molecular mechanism for the procentriole assembly.

BDNF axonal signaling regulates protein synthesis in neuronal cell bodies leading to dendritic arborization through dynein-dependent transport of signaling endosomes.