30 results found
    1. Immunology and Inflammation

    Exercise training at different intensities induces heat stress, disrupts barrier function and alters microbiota in the gut of mice

    Puqiao Lian, Artemiy Kovynev ... Saskia Braber
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation

    IL-2 enhances effector function but suppresses follicular localization of CD8+ T cells in chronic infection

    Yaping Chen, Pengcheng Zhou ... Di Yu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Amphibian mast cells serve as barriers to chytrid fungus infections

    Kelsey A Hauser, Christina N Garvey ... Leon Grayfer
    Enriching amphibian, Xenopus laevis, cutaneous mast cells confers protection against Batrachochytrium dendrobatidis chytrid fungus infections.
    1. Immunology and Inflammation

    Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

    Preksha Gaur, Yesheswini Rajendran ... Chittur Srikanth
    Rab7-mediated changes in goblet cell function play a crucial role in triggering gut inflammation during colitis.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Energetics of the microsporidian polar tube invasion machinery

    Ray Chang, Ari Davydov ... Manu Prakash
    Unraveling the ultrafast polar tube ejection in microsporidia reveals extreme cellular hydraulics, providing a data-driven model for infectious cargo transport, with implications for physical approaches to understanding microsporidia transmission.
    1. Cell Biology

    A single-cell transcriptome atlas of pig skin characterizes anatomical positional heterogeneity

    Qin Zou, Rong Yuan ... Yanzhi Jiang
    The heterogeneity in molecule and function of three main cell types of smooth muscle cells, endothelial cells, and fibroblasts from both different anatomical sites of pig skin was comprehensively exposited.
    1. Microbiology and Infectious Disease

    Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface

    Liheng Yang, Eleanor C Semmes ... Carolyn B Coyne
    Organoids developed from matched human placental tissue define differences in antiviral signaling between cell types comprising the maternal-fetal interface.
    1. Cell Biology
    2. Medicine

    Inhibition of the sodium-dependent HCO3- transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype

    Vinciane Saint-Criq, Anita Guequén ... Carlos A Flores
    The reduction of bicarbonate secretion into the airways reproduces cystic fibrosis-like features, independently of chloride secretion.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females

    Bretta Hixson, Xiao-Li Bing ... Nicolas Buchon
    RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.

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