670 results found
    1. Epidemiology and Global Health

    Structure in the variability of the basic reproductive number (R0) for Zika epidemics in the Pacific islands

    Clara Champagne et al.
    Stochastic models able to reproduce both incidence and seroprevalence data for Zika outbreaks in the Pacific Islands estimate that the basic reproduction number (R0) is between 1.5 and 4.1.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Cell-to-cell infection by HIV contributes over half of virus infection

    Shingo Iwami et al.
    The human immunodeficiency virus HIV-1 primarily spreads between cells using a method called cell-to-cell infection, suggesting that this process may be a target for anti-viral drugs.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis

    Teja Turk et al.
    A method to assess the risk of self-sustained HIV transmission in heterosexuals from phylogenetic and epidemiological data is developed and, when applied to the Swiss HIV epidemic, shows that this risk is negligibly small for Switzerland.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Epidemiology: Promiscuous bacteria have staying power

    Ruth C Massey, Daniel J Wilson
    Being able to take up DNA from their environment might allow pneumococcal bacteria to colonize the human nose and throat for longer periods of time.
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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Phenotypic Diversity: Setting the bar

    Charles Y Feigin, Ricardo Mallarino
    Analyzing the genomes of rock pigeons demonstrates that genetic variation comes in many forms and can have unexpected origins.
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    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Point of View: Looking back and looking forward at Janelia

    Gerald M Rubin, Erin K O'Shea
    The Janelia Research Campus opened its doors 12 years ago: we describe the philosophy underpinning Janelia, the lessons learned, and plans for the future.
    1. Developmental Biology

    The Natural History of Model Organisms: An organismal perspective on C. intestinalis development, origins and diversification

    Matthew J Kourakis, William C Smith
    The life cycle and morphology of the sea squirt Ciona intestinalis shed light on vertebrate evolution.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: Advancing biology through a deeper understanding of zebrafish ecology and evolution

    David M Parichy
    The zebrafish is a premier model organism for biomedical research, with a rich array of tools and genomic resources, and combining these with a fuller appreciation of wild zebrafish ecology could greatly extend its utility in biological research.
    1. Ecology
    2. Plant Biology

    The Natural History of Model Organisms: Planting molecular functions in an ecological context with Arabidopsis thaliana

    Ute Krämer
    Research in molecular ecology and evolution is increasingly utilizing the model plant Arabidopsis thaliana, placing a spotlight on its natural history.
    1. Ecology
    2. Evolutionary Biology

    Evolution: Modeling evolutionary transitions in social insects

    Michael Doebeli, Ehab Abouheif
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