5,246 results found
    1. Medicine

    Point of View: Applied research won’t flourish without basic science

    Jon R Lorsch, Lawrence A Tabak, Monica M Bertagnolli
    Three senior figures at the US National Institutes of Health explain why the agency remains committed to supporting basic science and research.
  1. Point of View: Basic research at the epicenter of an epidemic

    William R Bishai
    William R Bishai, director of the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), argues that the best place to carry out research into a disease is in its midst.
    1. Medicine
    2. Neuroscience

    Point of View: Coordinating a new approach to basic research into Parkinson’s disease

    Randy Schekman, Ekemini AU Riley
    The ASAP initiative will incentivize collaboration between researchers and encourage open-science practices to improve our understanding of the biology underlying Parkinson's disease.
    1. Biochemistry and Chemical Biology
    2. Epidemiology and Global Health

    Association of egg consumption, metabolic markers, and risk of cardiovascular diseases: A nested case-control study

    Lang Pan, Lu Chen ... Liming Li
    The associations of egg consumption with metabolic markers and of these markers with cardiovascular disease (CVD) risk showed opposite directions, which may partially explain the protective effect of moderate egg consumption on CVD in the Chinese population.
    1. Neuroscience

    Predictive models for secondary epilepsy in patients with acute ischemic stroke within one year

    Jinxin Liu, Haoyue He ... Yongbing Deng
    Machine learning models effectively predict the risk of post-stroke epilepsy using extensive clinical data, offering new insights for improving patient management in clinical neurology.
    1. Neuroscience

    Introduction to the EQIPD quality system

    Anton Bespalov, René Bernard ... Thomas Steckler
    A system has been developed that supports generation of reliable basic biomedical research data while being open-access and lean with no negative impact on freedom of scientific exploration.
    1. Medicine
    2. Neuroscience

    Science Forum: Consensus-based guidance for conducting and reporting multi-analyst studies

    Balazs Aczel, Barnabas Szaszi ... Eric-Jan Wagenmakers
    Using multiple analysts to independently analyze the same dataset has the potential to explore and strengthen the robustness of results and conclusions in basic and applied research.
    1. Cancer Biology

    Science Forum: Is preclinical research in cancer biology reproducible enough?

    Patrick Bodilly Kane, Jonathan Kimmelman
    Results from the Reproducibility Project: Cancer Biology provide a picture of the rate of false positives in cancer preclinical research, but it is still not clear if research in this field is less reproducible than it should be.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    National Institutes of Health research project grant inflation 1998 to 2021

    Michael S Lauer, Joy Wang, Deepshikha Roychowdhury
    National Institutes of Health (NIH) grants have evolved over time, with a greater proportion of funds going to solicited projects, but inflation-adjusted costs have remained relatively stable following a brief increase during the NIH-doubling (1998-2003).
    1. Computational and Systems Biology
    2. Medicine

    Meta-Research: Author-level data confirm the widening gender gap in publishing rates during COVID-19

    Emil Bargmann Madsen, Mathias Wullum Nielsen ... Jens Peter Andersen
    The gender gap in publication productivity has increased during the COVID-19 pandemic, with potential implications for the careers of women working in research.

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