285 results found
    1. Neuroscience

    Exploring the expression patterns of palmitoylating and de-palmitoylating enzymes in the mouse brain using the curated RNA-seq database BrainPalmSeq

    Angela R Wild, Peter W Hogg ... Shernaz X Bamji
    A curated resource to study the brain RNA expression patterns of the genes that regulate palmitoylation is presented, alongside a detailed exploration of how these patterns can inform future research.
    1. Neuroscience

    Associative plasticity of granule cell inputs to cerebellar Purkinje cells

    Rossella Conti, Céline Auger
    Associative plasticity of proximal and distal granule cell inputs to Purkinje cells enables time dependent association of information from local and distant receptive fields.
    1. Neuroscience

    A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes

    Blaise Robert, Eyal Y Kimchi ... Daniel B Polley
    Activity levels in anterior and posterior cholinergic basal forebrain neurons are associated with distinct aspects of global brain state, sensory salience, reward expectation, and aversive reinforcement learning.
    1. Neuroscience

    A striatal circuit balances learned fear in the presence and absence of sensory cues

    Michael Kintscher, Olexiy Kochubey, Ralf Schneggenburger
    Direct- and indirect pathway neurons of the posterior striatum display divergent in vivo and ex vivo plasticity after fear learning, and differentially modulate defensive behaviors displayed in the presence, and absence of threat-predicting sensory cues.
    1. Neuroscience

    Decoding a neural circuit controlling global animal state in C. elegans

    Patrick Laurent, Zoltan Soltesz ... Mario de Bono
    Sensory neurons that monitor ambient oxygen control a cascade of responses across multiple layers of interneurons to switch the global state of the nematode C. elegans, reprogramming behavior and gene expression to enable escape from or adaptation to surface exposure.
    1. Neuroscience

    Learning of state representation in recurrent network: the power of random feedback and biological constraints

    Takayuki Tsurumi, Ayaka Kato ... Kenji Morita
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology
    2. Developmental Biology

    Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

    Tarun Kumar, Leo Blondel, Cassandra G Extavour
    Regulatory networks of genes controlling different aspects of insect reproduction have been identified by a systems-level analysis of quantitative phenotypic information obtained from the loss of individual cell signaling genes.
    1. Computational and Systems Biology
    2. Developmental Biology

    Elastic force restricts growth of the murine utricle

    Ksenia Gnedeva, Adrian Jacobo ... A J Hudspeth
    Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.
    1. Neuroscience

    Goal-directed motor actions drive acetylcholine dynamics in sensory cortex

    Jing Zou, Jan Willem de Gee ... Samuel Andrew Hires
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid

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