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Neural encoding of actual and imagined touch within human posterior parietal cortex
Srinivas Chivukula et al.
Single neurons in human posterior parietal cortex encode actual and imagined touch within a shared neural substrate.
Dual midbrain and forebrain origins of thalamic inhibitory interneurons
Polona Jager et al.
Thalamic interneurons in the mouse thalamus are often overlooked because of their extremely low numbers, however they are developmentally complex and related to those of larger-brained species.
Genetics and Genomics
Microbiology and Infectious Disease
An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations
Marcos H de Moraes et al.
Interbacterial interactions can promote mutagenesis, and possibly adaptation, when intoxicated cells survive exposure to type VI secretion-delivered DNA deaminase toxins.
Computational and Systems Biology
Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin
Lucile Megret et al.
Cell-type-specific molecular systems mapping reveals that striatal neuron degeneration in Huntington's disease is primarily driven by the loss of homeostatic responses.
Genetics and Genomics
Education and Outreach: March Mammal Madness and the power of narrative in science outreach
Katie Hinde et al.
Hypothetical battles between animals can be used to interest the general public in biology.
Evolutionary shifts in taste coding in the fruit pest
Hany KM Dweck et al.
The evolutionary transition of the agricultural pest
to egg laying on ripe fruits was paralleled with several gustatory innovations.
A flagellate-to-amoeboid switch in the closest living relatives of animals
Thibaut Brunet et al.
The closest living relatives of animals, the choanoflagellates, switch from a flagellate to an amoeboid phenotype under confinement.
Structural Biology and Molecular Biophysics
Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets
Valeria Zoni et al.
In parallel to protein-driven processes, characteristic physicochemical properties of the endoplasmic reticulum membrane modulate intracellular fat accumulation and lipid droplet formation.
Coupling between fast and slow oscillator circuits in
Daniel Powell et al.
The mechanism that couples two rhythmic circuits is maintained over a large temperature range although both circuits are temperature-sensitive.
Adaptive evolution of nontransitive fitness in yeast
Sean W Buskirk et al.
A series of selective events, each improving fitness relative to an immediate predecessor, can result in organisms that are less fit compared to a distant ancestor.
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