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Microbiology and Infectious Disease
Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures
Mauricio Seguel et al.
In years with colder ocean temperatures, fur seal pups receive more maternal care and have a better energy balance, clearing hookworm infection earlier, which increases their chances of survival.
Peptidoglycan-dependent NF-κB activation in a small subset of brain octopaminergic neurons controls female oviposition
Ambra Masuzzo et al.
The universal bacteria cell wall component peptidoglycan impacts the egg-laying behavior of infected
females by directly modulating the activity of few brain octopaminergic neurons.
Point of View: Competency-based assessment for the training of PhD students and early-career scientists
Michael F Verderame et al.
A method to assess the training of scientists, based on a set of 10 core competencies, is proposed.
Research: Theory, models and biology
Wenying Shou et al.
Theoretical ideas have a rich history in many areas of biology, and new theories and mathematical models have much to offer in the future.
Meta-Research: A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals
Diana Herrera-Perez et al.
An analysis of more than 3000 randomized controlled trials published in JAMA, the Lancet and NEJM has identified 396 medical reversals.
The Natural History of Model Organisms: Insights into the evolution of social systems and species from baboon studies
Julia Fischer et al.
Wild baboons are an excellent model to study complex evolutionary processes such as speciation and hybridization, as well as the links between sociality, longevity and reproductive success.
Point of View: Coordinating a new approach to basic research into Parkinson’s disease
Randy Schekman, Ekemini AU Riley
The ASAP initiative will incentivize collaboration between researchers and encourage open-science practices to improve our understanding of the biology underlying Parkinson's disease.
Research: The readability of scientific texts is decreasing over time
Pontus Plavén-Sigray et al.
Scientific abstracts have become less readable over the past 130 years, in part because recent texts include more general scientific jargon than older texts.
Meta-Research: A 10-year follow-up study of sex inclusion in the biological sciences
Nicole C Woitowich et al.
Sex-inclusive research practices have increased in many biological disciplines over the past decade, yet critical sex-based analyses and reporting have remained stagnant in most of these disciplines.
Computational and Systems Biology
Research: Bias in the reporting of sex and age in biomedical research on mouse models
Oscar Flórez-Vargas et al.
A text-mining study suggests that about half of the papers reporting the results of experiments on mice do not report the sex and age of the mice.
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