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    1. Neuroscience

    PBN-PVT projections modulate negative affective states in mice

    Ya-Bing Zhu, Yan Wang ... Di Mu
    The parabrachial nucleus-thalamic paraventricular nucleus pathway is critical for modulating affective states in mice.
    1. Neuroscience

    A transient cortical state with sleep-like sensory responses precedes emergence from general anesthesia in humans

    Laura D Lewis, Giovanni Piantoni ... Patrick L Purdon
    Intracranial recordings of human brain activity during awakening from general anesthesia exhibit a brief brain state not seen during loss of consciousness, in which stimuli elicit large electrophysiological responses that resemble those seen in sleep.
    1. Neuroscience

    Acetic acid activates distinct taste pathways in Drosophila to elicit opposing, state-dependent feeding responses

    Anita V Devineni, Bei Sun ... Richard Axel
    A single taste input, acetic acid, elicits opposing behavioral outputs depending on a fly's hunger state.
    1. Neuroscience

    Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle

    Heng Zhou, Kevin R Neville ... Stephen N Gomperts
    Dynamic calcium activity in the hippocampus changes markedly across behavioral and physiological states and depends on muscarinic acetylcholine receptor activation.
    1. Ecology
    2. Neuroscience

    Genetic variation in the social environment affects behavioral phenotypes of oxytocin receptor mutants in zebrafish

    Diogo Ribeiro, Ana Rita Nunes ... Rui F Oliveira
    Individual social behavior results from the interaction between the individuals own oxytocin receptor genotype and the oxytocin receptor genotypes of other individuals present in its social environment.
    1. Neuroscience

    Optogenetic dissection of descending behavioral control in Drosophila

    Jessica Cande, Shigehiro Namiki ... Gordon J Berman
    Optogenetically activated individual descending neurons in Drosophila melanogaster drive varied stereotyped motor patterns that are often influenced by the animal's initial behavioral state.
    1. Neuroscience

    Monkeys exhibit human-like gaze biases in economic decisions

    Shira M Lupkin, Vincent B McGinty
    A novel animal model of economic decision-making captures complex patterns of choice behavior similar to those of humans, opening the way for mechanistic studies to probe the neural basis for this important form of executive function.
    1. Neuroscience

    Decoding a neural circuit controlling global animal state in C. elegans

    Patrick Laurent, Zoltan Soltesz ... Mario de Bono
    Sensory neurons that monitor ambient oxygen control a cascade of responses across multiple layers of interneurons to switch the global state of the nematode C. elegans, reprogramming behavior and gene expression to enable escape from or adaptation to surface exposure.
    1. Neuroscience

    Homeostatic reinforcement learning for integrating reward collection and physiological stability

    Mehdi Keramati, Boris Gutkin
    A mathematical model built around the assumption that the desire to maintain internal homeostasis drives the behavior of animals, by affecting their learning processes, can explain many real-world behaviors, including some that might otherwise appear irrational.