3,020 results found
    1. Ecology
    2. Microbiology and Infectious Disease

    Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures

    Mauricio Seguel et al.
    In years with colder ocean temperatures, fur seal pups receive more maternal care and have a better energy balance, clearing hookworm infection earlier, which increases their chances of survival.
    1. Ecology

    The lost world of Cuatro Ciénegas Basin, a relictual bacterial niche in a desert oasis

    Valeria Souza et al.
    At Cuatro Ciénegas, the ancestral niche conditions of the ancient shores of Laurentia persisted along with its microbial communities that have been coevolving for a very long time.
    1. Computational and Systems Biology
    2. Developmental Biology

    A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

    Kenneth KH Ng et al.
    The timing and outcome of mammalian cell lineage decisions can be controlled by slow, stochastic events on individual regulatory gene loci.
    1. Neuroscience

    Bright multicolor labeling of neuronal circuits with fluorescent proteins and chemical tags

    Richi Sakaguchi et al.
    A bright and stochastic multicolor labeling method, Tetbow, facilitates millimeters-scale reconstructions of neuronal circuits at a large scale using tissue clearing.
    1. Cell Biology
    2. Neuroscience

    Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones

    Nickolai V Vysokov et al.
    Lasso and latrophilin-1 interact across the synapse, while shed Lasso binds latrophilin-1 on distant growth cones and attracts them, providing a universal mechanism for short- and long-range axonal guidance.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community

    Kevin D'hoe et al.
    Human gut bacteria alter their metabolism in response to each other's presence, which causes their community dynamics to deviate from predictions that are based on mono-culture data.
    1. Computational and Systems Biology
    2. Neuroscience

    Inhibition enhances spatially-specific calcium encoding of synaptic input patterns in a biologically constrained model

    Daniel B Dorman et al.
    Inhibition enhances the spatial specificity of high calcium influx for cooperatively stimulated synapses, suggesting that inhibitory inputs may regulate both synapse-specific and heterosynaptic plasticity to support learning and memory.
    1. Evolutionary Biology
    2. Neuroscience

    Recalibrating timing behavior via expected covariance between temporal cues

    Benjamin J De Corte et al.
    Rats act as if they expect that the delays associated with temporal cues will covary due to a common causal factor.

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