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    1. Computational and Systems Biology

    The functional form of value normalization in human reinforcement learning

    Sophie Bavard, Stefano Palminteri
    Challenging a popular theory in neuroeconomics, a computational cognitive study provides evidence against divisive normalization, a supposedly canonical neural computation, in favor of an alternative account, range normalization, in the context of value learning.
    1. Microbiology and Infectious Disease

    Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota

    Daniel Hoces, Giorgia Greter ... Emma Slack
    Neutral tagging and detailed analysis of bacterial growth kinetics can quantify the mechanisms of colonization resistance in differently colonized animals.
    1. Neuroscience

    Internal neural states influence the short-term effect of monocular deprivation in human adults

    Yiya Chen, Yige Gao ... Jiawei Zhou
    Having the eye open under the patch, even though this does not change the exogenous stimulation because the eye is occluded, will result in an enhanced short-term effect for ocular dominance due to the internal neural states.
    1. Cell Biology
    2. Developmental Biology

    Aurora A and cortical flows promote polarization and cytokinesis by inducing asymmetric ECT-2 accumulation

    Katrina M Longhini, Michael Glotzer
    Centrosomal Aurora A (AIR-1), together with cortical actomyosin flows, induces polarization of ECT-2, the activator of RHO-1, during polarization and cytokinesis, in order to promote furrow formation.
    1. Neuroscience

    Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula

    Efe Soyman, Rune Bruls ... Valeria Gazzola
    Intracranial recordings indicate that the insula encodes, in a partially intermixed layout, both static and dynamic cues from different body parts that reflect the intensity of pain experienced by others.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    PH domain-mediated autoinhibition and oncogenic activation of Akt

    Hwan Bae, Thibault Viennet ... Philip A Cole
    Structural and biochemical analysis of semisynthetic Akt forms and mutants has revealed the importance of a key interaction network involving Arg86, Glu17, and Tyr18 that controls Akt conformation and activity.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evolution of host-microbe cell adherence by receptor domain shuffling

    EmilyClare P Baker, Ryan Sayegh ... Matthew F Barber
    Rapid evolution and gene conversion of a primate cell surface receptor family blocks recognition by pathogenic bacteria.
    1. Cell Biology

    Src activates retrograde membrane traffic through phosphorylation of GBF1

    Joanne Chia, Shyi-Chyi Wang ... Frederic A Bard
    Src phosphorylates GBF1, promoting binding of the Sec7 domain to Arf1 and the formation of GALNTs containing tubules emanating from the Golgi.
    1. Neuroscience

    Cortical signatures of precision grip force control in children, adolescents, and adults

    Mikkel Malling Beck, Meaghan Elizabeth Spedden ... Jesper Lundbye-Jensen
    Precise motor control is supported by connectivity within a cortical grasping network from childhood to adulthood, but older individuals display more top-down control and superior motor performance compared to children.
    1. Neuroscience

    Spatially displaced excitation contributes to the encoding of interrupted motion by a retinal direction-selective circuit

    Jennifer Ding, Albert Chen ... Wei Wei
    The direction-selective circuit in the retina adjusts the contributions of excitatory and inhibitory mechanisms under different stimulus conditions to generate context-dependent neural representations of visual features.