7,053 results found
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells

    João D Dias, Tiago Rito ... Ana Pombo
    Lysine mono- and di-methylation are two novel post-translational modifications of RNA polymerase II, which are enriched at promoters of active genes, precede lysine acetylation and mark early stages of transcription.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Consistent and correctable bias in metagenomic sequencing experiments

    Michael R McLaren, Amy D Willis, Benjamin J Callahan
    A mathematical model of bias in marker-gene and metagenomic sequencing measurements explains systematic errors in defined mixtures of microbial species, and enables quantitative and reproducible investigation of biological communities.
    1. Neuroscience

    Humans strategically shift decision bias by flexibly adjusting sensory evidence accumulation

    Niels A Kloosterman, Jan Willem de Gee ... Johannes Jacobus Fahrenfort
    Decision-makers are able to intentionally control neural excitability to strategically bias sensory evidence accumulation towards the decision bound that maximizes reward within a given ecological context.
    1. Developmental Biology

    A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation

    André Dias, Anastasiia Lozovska ... Moises Mallo
    During vertebrate axial extension, the tail bud originates from the activation of a developmental module in a subset of axial progenitors, concurrent but different to gastrulation.
    1. Biochemistry and Chemical Biology

    The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression

    Chunjing Bian, Qiang Chen, Xiaochun Yu
    Repression of gene expression by the histone methyltransferase G9a is guided by two zinc finger proteins that can recognize consensus sequences in DNA.
  1. Meta-Research: Weak evidence of country- and institution-related status bias in the peer review of abstracts

    Mathias Wullum Nielsen, Christine Friis Baker ... Jens Peter Andersen
    A preregistered survey experiment spanning six disciplines has found weak evidence of bias in favour of authors from high-status countries and institutions.
    1. Immunology and Inflammation

    TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance

    Marije Baas, Alix Besançon ... Sylvaine You
    The interplay between the cytokine TGFβ and the PD-1/PD-L1 pathway promotes CD8+ T cell anergy and tolerance towards transplanted tissues.
    1. Neuroscience

    Neural correlates of ingroup bias for prosociality in rats

    Inbal Ben-Ami Bartal, Jocelyn M Breton ... Daniela Kaufer
    A distinct neural network, including the nucleus accumbens as a central hub, is active when rats are exposed to trapped ingroup members they had previously helped escape a trap, but not for outgroup members who had not been helped.
    1. Neuroscience

    Boosts in brain signal variability track liberal shifts in decision bias

    Niels A Kloosterman, Julian Q Kosciessa ... Douglas D Garrett
    Modulation of moment-to-moment irregularity of neural activity closely tracks our ability to flexibly adapt decision biases to the environment.
    1. Cell Biology

    Pericentrin-mediated SAS-6 recruitment promotes centriole assembly

    Daisuke Ito, Sihem Zitouni ... Mónica Bettencourt-Dias
    Newly discovered interaction between fission yeast SPB and animal centriole components reveals that pericentrin not only functions as a microtubule-nucleator, but also promotes centriole assembly in animals.

Refine your results by:

Type
Research categories