Lysine mono- and di-methylation are two novel post-translational modifications of RNA polymerase II, which are enriched at promoters of active genes, precede lysine acetylation and mark early stages of transcription.
Michael R McLaren, Amy D Willis, Benjamin J Callahan
A mathematical model of bias in marker-gene and metagenomic sequencing measurements explains systematic errors in defined mixtures of microbial species, and enables quantitative and reproducible investigation of biological communities.
Niels A Kloosterman, Jan Willem de Gee ... Johannes Jacobus Fahrenfort
Decision-makers are able to intentionally control neural excitability to strategically bias sensory evidence accumulation towards the decision bound that maximizes reward within a given ecological context.
During vertebrate axial extension, the tail bud originates from the activation of a developmental module in a subset of axial progenitors, concurrent but different to gastrulation.
Repression of gene expression by the histone methyltransferase G9a is guided by two zinc finger proteins that can recognize consensus sequences in DNA.
Mathias Wullum Nielsen, Christine Friis Baker ... Jens Peter Andersen
A preregistered survey experiment spanning six disciplines has found weak evidence of bias in favour of authors from high-status countries and institutions.
Inbal Ben-Ami Bartal, Jocelyn M Breton ... Daniela Kaufer
A distinct neural network, including the nucleus accumbens as a central hub, is active when rats are exposed to trapped ingroup members they had previously helped escape a trap, but not for outgroup members who had not been helped.
Newly discovered interaction between fission yeast SPB and animal centriole components reveals that pericentrin not only functions as a microtubule-nucleator, but also promotes centriole assembly in animals.