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    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
    1. Epidemiology and Global Health

    Disease Risk: Mapping the emerging burden of dengue

    Oliver Brady
    The first nationally-representative survey of dengue has revealed the growing burden of the disease in Bangladesh.
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    1. Computational and Systems Biology

    Point of View: Data science for the scientific life cycle

    Daphne Ezer, Kirstie Whitaker
    Each stage of the scientific life cycle stands to benefit from the introduction of data science techniques.
    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Brain Size: Gene losses did not stop the evolution of big brains

    Cristian Cañestro, Vittoria Roncalli
    Elephants and fruit bats have evolved large brains even though they have lost a gene that is fundamental to the supply of energy to the brain when glucose is not available.
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    1. Cell Biology
    2. Neuroscience

    2018 Gairdner Awards: The past, present and future of light-gated ion channels and optogenetics

    Sheena A Josselyn
    Research into light-gated ion channels called channelrhodospins laid the foundations for the development of optogenetics, a technique that has gone on to revolutionize neuroscience.
    1. Biochemistry and Chemical Biology

    Intracellular Diffusion: How bacteria keep proteins moving

    Conrad W Mullineaux
    Bacteria contain large numbers of negatively-charged proteins to avoid the electrostatic interactions with ribosomes that would dramatically reduce protein diffusion.
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  1. Peer Review: Searching for the one

    Helga Groll
    The views of peers are important when applying for a faculty position, but so are research plans and being a good 'fit'.
  2. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.