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    1. Neuroscience

    The OpenNeuro resource for sharing of neuroscience data

    Christopher J Markiewicz, Krzysztof J Gorgolewski ... Russell Poldrack
    OpenNeuro is a data sharing archive that provides a platform for the free and open sharing of a broad range of neuroscience data types.
    1. Neuroscience

    Science Forum: How failure to falsify in high-volume science contributes to the replication crisis

    Sarah M Rajtmajer, Timothy M Errington, Frank G Hillary
    An increased emphasis on falsification – the direct testing of strong hypotheses – will lead to faster progress in science by allowing well-specified hypotheses to be eliminated.
    1. Computational and Systems Biology
    2. Neuroscience

    Discovering and deciphering relationships across disparate data modalities

    Joshua T Vogelstein, Eric W Bridgeford ... Cencheng Shen
    Multiscale Graph Correlation, an interpretable hypothesis test with strong theoretical guarantees for discerning relationships in complex data, requires about half the sample size as other methods, whilst maintaining computational tractability.
    1. Neuroscience

    Multiple decisions about one object involve parallel sensory acquisition but time-multiplexed evidence incorporation

    Yul HR Kang, Anne Löffler ... Michael N Shadlen
    When making two decisions about one object, two streams of information can be acquired in parallel but must be incorporated into the two decisions serially, consistent with a central bottleneck.
    1. Epidemiology and Global Health

    Changes in transmission of Enterovirus D68 (EV-D68) in England inferred from seroprevalence data

    Margarita Pons-Salort, Ben Lambert ... Nicholas C Grassly
    Serocatalytic models applied to seroprevalence data from England reveal an increase in Enterovirus D68 transmission that occurred before 2011.
    1. Neuroscience

    Charting brain growth and aging at high spatial precision

    Saige Rutherford, Charlotte Fraza ... Andre F Marquand
    During an individual's lifetime, their brain undergoes a unique transformation that we have precisely mapped across thousands of people to create and share reference growth charts of the human brain's lifespan which allow for single subject exploration and inference.
    1. Neuroscience

    Design issues and solutions for stop-signal data from the Adolescent Brain Cognitive Development (ABCD) study

    Patrick G Bissett, McKenzie P Hagen ... Russell A Poldrack
    Problematic design features in the stop-signal task for the massive Adolescent Brain Cognitive Development (ABCD) study undermine analyses of the shared data, but can be mitigated with proposed solutions.
    1. Ecology
    2. Genetics and Genomics

    Viral dark matter and virus–host interactions resolved from publicly available microbial genomes

    Simon Roux, Steven J Hallam ... Matthew B Sullivan
    From public microbial genomes, VirSorter revealed 12,498 viral genome sequences that expand the map of the global virosphere and whose analyses improve understanding of viral taxonomy, evolution and virus-host interactions.
    1. Computational and Systems Biology
    2. Medicine

    Data mining methodology for response to hypertension symptomology—application to COVID-19-related pharmacovigilance

    Xuan Xu, Jessica Kawakami ... Majid Jaberi-Douraki
    Quantitative models and data-driven approaches developed for the COVID-19 pandemic and predicting SARS-Cov-2 comorbidities for high-risk populations including hypertension show that the future of large-scale biomedical science will be significantly underscored by data-driven decision-making and AI knowledge-based development and validation.
    1. Neuroscience

    Dynamic representation of 3D auditory space in the midbrain of the free-flying echolocating bat

    Ninad B Kothari, Melville J Wohlgemuth, Cynthia F Moss
    Neurons in the midbrain superior colliculus of free-flying echolocating bats represent 3D sensory space, and the depth tuning of single neurons is modulated by an animal's active sonar inspection of physical objects in its environment.