148 results found
    1. Microbiology and Infectious Disease

    An orphan cbb3-type cytochrome oxidase subunit supports Pseudomonas aeruginosa biofilm growth and virulence

    Jeanyoung Jo et al.
    During growth in biofilms and host infection, the opportunistic pathogen Pseudomonas aeruginosa employs respiratory heterocomplexes that support extracellular electron shuttling and pathogenicity.
    1. Microbiology and Infectious Disease

    Structural basis of host recognition and biofilm formation by Salmonella Saf pili

    Longhui Zeng et al.
    SafDAA-SafDAA structure and functional characterizations reveal a pili-mediated inter-cellular oligomerization mechanism for bacterial aggregation and biofilm formation in Salmonella enterica.
    1. Microbiology and Infectious Disease

    Impaired respiration elicits SrrAB-dependent programmed cell lysis and biofilm formation in Staphylococcus aureus

    Ameya A Mashruwala et al.
    The absence of oxygen prompts Staphylococcus aureus cells to rupture resulting in increased formation of biofilms, which are the etiological agents of recurrent infections.
    1. Physics of Living Systems

    Mechanical instability and interfacial energy drive biofilm morphogenesis

    Jing Yan et al.
    Mechanical instabilities are shown to underlie the development of bacterial biofilm morphology, suggesting an ancient origin for mechano-morphogenesis, which is known to drive developmental processes in tissues in higher organisms.
    1. Ecology
    2. Microbiology and Infectious Disease

    Flow environment and matrix structure interact to determine spatial competition in Pseudomonas aeruginosa biofilms

    Carey D Nadell et al.
    The feedback between hydrodynamic flow conditions and biofilm spatial architecture drives competition in P. aeruginosa biofilms, and can explain variation in biofilm production observed among bacteria in natural environments.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms

    Jiunn CN Fong et al.
    Biofilm matrix protein RbmA controls biofilm architecture through binary structural switching and exopolysaccharide binding.
    1. Microbiology and Infectious Disease

    The horizontally-acquired response regulator SsrB drives a Salmonella lifestyle switch by relieving biofilm silencing

    Stuti K Desai et al.
    A response regulator acquired via lateral gene transfer has rewired an ancestral genetic circuitry and regulates alternative pathogenic lifestyles.
    1. Microbiology and Infectious Disease

    Biofilms: Take my breath away

    Vinai C Thomas, Paul D Fey
    A lack of oxygen activates a pathway that causes the bacterial cell wall to break down, which, in turn, aids bacterial biofilm development.
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    1. Physics of Living Systems

    Biophysics: Common concepts for bacterial collectives

    Hannah Jeckel et al.
    The expansion of bacterial swarms and the spreading of biofilms can be described by a unified biophysical theory that involves both active and passive processes.
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    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Biofilms: Flipping the switch

    Xavier Pierrat, Alexandre Persat
    A structural switch controls the architecture of Vibrio cholerae biofilms by mediating the interactions between two matrix components.
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