679 results found
    1. Epidemiology and Global Health

    Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

    Daniel W Belsky et al.
    Methylation pace of aging is a novel measure requiring only a blood sample that clinical-trial and observational studies can use to test if treatments modify how fast participants are aging.
    1. Epidemiology and Global Health

    Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up

    Xia Li et al.
    Biological ages have the potential to provide aging-related information beyond chronological age and can be predictive of mortality independently of both chronological age and different types of biological ages.
    1. Epidemiology and Global Health

    Aging and Geroscience: Putting epigenetic biomarkers to the test for clinical trials

    Jamie N Justice, Stephen B Kritchevsky
    Reliable biomarkers are needed to test the effectiveness of interventions intended to improve health and extend lifespan.
    Insight
    Available as:
    • HTML
    • PDF
    1. Epidemiology and Global Health

    Mortality: The challenges of estimating biological age

    Alexey Moskalev
    A comparison of nine different approaches over a period of 20 years reveals the most promising indicators for biological age.
    Insight
    Available as:
    • HTML
    • PDF
    1. Chromosomes and Gene Expression

    A whole lifespan mouse multi-tissue DNA methylation clock

    Margarita V Meer et al.
    A robust mouse multi-tissue age predictor is presented that can be used to assess the DNA methylation age of mouse tissues and test the effects of longevity interventions.
  1. Modelling metabolism: an interview with Keren Yizhak

    Keren Yizhak majored in computational biology at the Hebrew University of Jerusalem and is currently a PhD student at the School of Computer Science at Tel-Aviv University, where she uses computational techniques to study biological phenomena, focusing on the metabolic changes that occur in cells during cancer and ageing. She will move to the Broad Institute at Harvard and MIT in March 2015 to begin her first postdoctoral position. Her main interest outside of science is ballet dancing, which she finds a source of inspiration and discipline.
    1. Developmental Biology
    2. Neuroscience
    Pond snail illustration

    The Natural History of Model Organisms: The unlimited potential of the great pond snail, Lymnaea stagnalis

    István Fodor et al.
    The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.
    1. Neuroscience

    Imaging: The many facets of brain aging

    Lars Nyberg, Anders Wåhlin
    Applying big-data analytic techniques to brain images from 18,707 individuals is shedding light on the influence of aging on the brain.
    Insight
    Available as:
    • HTML
    • PDF
    1. Developmental Biology
    2. Genetics and Genomics

    Aging and Longevity: Short and sweet

    Coleen T Murphy
    A truncated version of the only insulin receptor in C. elegans has been discovered.
    Insight
    Available as:
    • HTML
    • PDF

Refine your results by:

Type
Research categories