2,639 results found
    1. Evolutionary Biology

    Plasticity and evolutionary convergence in the locomotor skeleton of Greater Antillean Anolis lizards

    Nathalie Feiner et al.
    A comparative and experimental research refutes the controversial hypothesis that plasticity played a major role in the convergent evolution of Anolis ecomorphs.
    1. Computational and Systems Biology
    2. Neuroscience

    Tuning movement for sensing in an uncertain world

    Chen Chen et al.
    Animals work in a world full of surprises, where using energy to position sensors proportional to the location's expected information avoids the pitfalls of positioning them at the information maxima.
    1. Neuroscience

    Activation of astrocytes in hippocampus decreases fear memory through adenosine A1 receptors

    Yulan Li et al.
    A new strategy of memory consolidation disruption based on astrocyte and purinergic signaling, which leads to persistent fear memory attenuation accompanied by reduced fear-related anxiety behavior.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Poultry farmer response to disease outbreaks in smallholder farming systems in southern Vietnam

    Alexis Delabouglise et al.
    Longitudinal monitoring of poultry farms in southern Vietnam reveals that when outbreaks occur with symptoms similar to highly pathogenic avian influenza, farmers respond by sending their chickens to market early.
    1. Structural Biology and Molecular Biophysics

    Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions

    Connor J Thompson et al.
    A combined experimental and computational approach was developed to understand lateral interactions between membrane-bound proteins and used to quantify the contributions of specific and non-specific interactions to cadherin cis-binding kinetics.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Genetic mapping of etiologic brain cell types for obesity

    Pascal N Timshel et al.
    Unbiased computational integration of single-cell- and human genetics data shows that susceptibility to obesity is driven by a broad set of neuronal populations across the brain.
    1. Computational and Systems Biology

    Removing unwanted variation with CytofRUV to integrate multiple CyTOF datasets

    Marie Trussart et al.
    CytofRUV is a computational algorithm that effectively enables batch effect reduction in multiple CyTOF batches with an adaptable normalisation method and an R-Shiny application with diagnostics plots.
    1. Neuroscience

    Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit

    Javier Díaz-Alonso et al.
    Despite being the key element of the classic model for excitatory synaptic plasticity, the cytoplasmic AMPA receptor C-tail is not required for hippocampal LTP.
    1. Cell Biology

    WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity

    Emmanuelle Steib et al.
    Centriole integrity is ensured by the connection between the inner scaffold and microtubule triplets through POC16/WDR90 proteins.
    1. Developmental Biology

    Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network

    Shreyasi Mukherjee et al.
    Genomic analysis of Xenopus gastrula reveal that the transcription factor Sox17 interacts with the Wnt signaling effector ß-catenin on enhancers to regulate the transcriptional program underlying endoderm germ layer formation.

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